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Advanced filters: Author: Natalia von Muhlinen Clear advanced filters

Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion

Galectin 8, a cytosolic lectin, is shown to function as a danger receptor that detects damaged vesicles and protects cells from bacterial infection by inducing autophagy.

Teresa L. M. Thurston
Michal P. Wandel
Felix Randow
Research15 Jan 2012
Nature

Volume: 482, P: 414-418
The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria

Polyubiquitin moieties often accumulate on bacteria that colonize the cytoplasm of mammalian cells. Randow and co-workers find that the protein NDP52 recognizes these ubiquitin moieties, and is needed for the control and autophagy of cytoplasmic bacteria.

Teresa L M Thurston
Grigory Ryzhakov
Felix Randow
Research11 Oct 2009
Nature Immunology

Volume: 10, P: 1215-1221
Distinct functions of wild-type and R273H mutant Δ133p53α differentially regulate glioblastoma aggressiveness and therapy-induced senescence

Sebastien M. Joruiz
Natalia Von Muhlinen
Curtis C. Harris
ResearchOpen Access27 Jun 2024
Cell Death & Disease

Volume: 15, P: 1-11
Acidovorax temperans skews neutrophil maturation and polarizes Th17 cells to promote lung adenocarcinoma development

Joshua K. Stone
Natalia von Muhlinen
Curtis C. Harris
ResearchOpen Access03 Apr 2024
Oncogenesis

Volume: 13, P: 1-16
p53 isoforms regulate premature aging in human cells

Natalia von Muhlinen
Izumi Horikawa
Curtis C. Harris
Research12 Feb 2018
Oncogene

Volume: 37, P: 2379-2393