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Showing 1–7 of 7 results
Advanced filters: Author: Natalija Novak Clear advanced filters

  • Genome-wide ancient DNA data from individuals from the Middle Bronze Age to Iron Age documents large-scale movement of people from the European continent between 1300 and 800 bc that was probably responsible for spreading early Celtic languages to Britain.

    • Nick Patterson
    • Michael Isakov
    • David Reich
    Research
    Nature
    Volume: 601, P: 588-594

  • IgE-FcεRI complex formation represents a critical step in the initiation of allergic responses. Conformational changes involving the Cε2 domain may underlie the persistent activation of FcεRI-bearing cells.

    • Natalija Novak
    • Thomas Bieber
    News & Views
    Nature Immunology
    Volume: 3, P: 607-608

  • This large-scale genome-wide association analysis of subjects with asthma, hay fever or eczema provides insights into the shared genetic basis of these allergic diseases. The findings suggest that these diseases partly co-occur because they share many genetic risk variants that dysregulate the expression of immune-related genes.

    • Manuel A Ferreira
    • Judith M Vonk
    • Lavinia Paternoster
    Research
    Nature Genetics
    Volume: 49, P: 1752-1757

  • Young-Ae Lee and colleagues report results of a genome-wide association study for atopic dermatitis. They identify a risk locus on chromosome 11q13 in a region previously associated with risk of Crohn's disease.

    • Jorge Esparza-Gordillo
    • Stephan Weidinger
    • Andreas Ruether
    Research
    Nature Genetics
    Volume: 41, P: 596-601