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Showing 1–2 of 2 results
Advanced filters: Author: Natasja Barki Clear advanced filters

  • An ‘intracrine’ signaling mechanism is proposed whereby a G-protein-coupled receptor (free fatty acid receptor 4) senses locally released fatty acids on intracellular membranes associated with lipid droplets to efficiently regulate lipolysis in adipocytes.

    • Shannon L. O’Brien
    • Emma Tripp
    • Davide Calebiro
    ResearchOpen Access
    Nature Chemical Biology
    Volume: 22, P: 109-119

  • A chemogenomic approach to explore activity of the free fatty acid receptor FFA2 independently of the related FFA3 shows that FFA2 in differentiated adipocytes and colonic crypt cells in mice is responsible for regulated lipolysis and GLP-1 release.

    • Daniele Bolognini
    • Natasja Barki
    • Graeme Milligan
    Research
    Nature Chemical Biology
    Volume: 15, P: 489-498