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Showing 1–2 of 2 results
Advanced filters: Author: Nathan A. Ewing-Crystal Clear advanced filters

  • Spatial transcriptomic studies and lineage tracing reveal that, after brain injury, transient profibrotic fibroblasts develop from existing brain fibroblasts, infiltrate lesions, regulate the local immune response and lead to beneficial scar tissue formation.

    • Nathan A. Ewing-Crystal
    • Nicholas M. Mroz
    • Ari B. Molofsky
    ResearchOpen Access
    Nature
    P: 1-11

  • CD123, the interleukin-3 receptor alpha chain, is aberrantly expressed in acute myeloid leukemia blasts and leukemia stem cells. Here the authors report the design and characterize the anti-tumor activity of allogeneic CD123-targeted CAR-T cells as a therapeutic approach for acute myeloid leukemia.

    • Mayumi Sugita
    • Roman Galetto
    • Monica L. Guzman
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-11