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Showing 1–2 of 2 results
Advanced filters: Author: Nathan Fraikin Clear advanced filters

  • pOXA-48 plasmids have emerged as key vectors of carbapenem resistance within Enterobacteriaceae. In this study, the authors use a transposon sequencing (Tn-seq) approach to identify genetic determinants critical for plasmid stability and conjugative transfer.

    • Yannick Baffert
    • Nathan Fraikin
    • Sarah Bigot
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-13

  • Toxin–antitoxin systems are composed of a toxin that inhibits an essential cellular process and an antitoxin that counteracts its cognate toxin. In this Review, Van Melderen and colleagues summarize the recent progress in understanding the biology and evolution of these small genetic elements, and discuss how genomic conflicts could shape the diversification of toxin–antitoxin systems.

    • Dukas Jurėnas
    • Nathan Fraikin
    • Laurence Van Melderen
    Reviews
    Nature Reviews Microbiology
    Volume: 20, P: 335-350