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Showing 1–2 of 2 results
Advanced filters: Author: Nathaniel Talledge Clear advanced filters

  • Cryo-EM structures of human ESCRT-III proteins forming membrane-bound and membrane-free filaments show how CHMP1B and IST1 polymerize sequentially, driving membrane tubulation, constriction and bilayer thinning, leading to membrane fission.

    • Henry C. Nguyen
    • Nathaniel Talledge
    • Adam Frost
    Research
    Nature Structural & Molecular Biology
    Volume: 27, P: 392-399

  • ESCRT-III proteins assemble into ubiquitous membrane-remodeling polymers during many cellular processes. Here, the authors use cryo-ET, cryo-EM and mathematical modeling to reveal how the shape of the helical membrane tube arises from the assembly of two distinct bundles of helical filaments.

    • Joachim Moser von Filseck
    • Luca Barberi
    • Aurélien Roux
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-9