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Showing 1–3 of 3 results
Advanced filters: Author: Navin Gopaldass Clear advanced filters
  • Retromer complex cooperates with Vps5 and Vps17 in yeast to traffic transmembrane proteins. Here, the authors present structural and functional studies that reveal the mechanism of Retromer and Vps5 interaction.

    • Kai-En Chen
    • Vikas A. Tillu
    • Brett M. Collins
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-19
  • In this work, the authors determined the cryo-EM structures of autophagy-related protein 18 organized in helical tubes and provide insights into the molecular framework for the positioning of downstream components of the autophagy machinery.

    • Daniel Mann
    • Simon A. Fromm
    • Carsten Sachse
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-13
  • Endosomes function as sorting stations that segregate cargo proteins into endosomal carriers, enabling their distribution to subcellular target compartments. Increasingly detailed structural insights have revealed how proteins, such as sorting nexins, assemble on endosomal membranes to form a coat that facilitates the formation and detachment of tubular carriers.

    • Navin Gopaldass
    • Kai-En Chen
    • Andreas Mayer
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 25, P: 765-783