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Showing 1–3 of 3 results
Advanced filters: Author: Navin Pokala Clear advanced filters

  • The structure of the N-terminal actin binding domain of human f imbrin offers the first view of an F-actin crosslinking protein and is representative of the conserved actin binding domain found in the largest family of crosslinking proteins. This domain is composed of two calponin homology domains and allows for the mapping of residues implicated in F-actin binding.

    • Sharon C. Goldsmith
    • Navin Pokala
    • Steven C. Almo
    Correspondence
    Nature Structural Biology
    Volume: 4, P: 708-712

  • Nematodes socialize during feeding on bacteria; this behaviour depends on sophisticated integration of multiple sensory cues by a subset of the animal's 302 neurons. The RMG neurons are identified as the hub for such computations. Non-synaptic communication through 'gap junctions' is the key to RMG's regulation of neighbouring sensory neurons such as ASK (which responds to pheromones, a functional architecture that could be generalized to several other neuronal circuits).

    • Evan Z. Macosko
    • Navin Pokala
    • Cornelia I. Bargmann
    Research
    Nature
    Volume: 458, P: 1171-1175