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Showing 1–4 of 4 results
Advanced filters: Author: Nayun Kim Clear advanced filters

  • High transcription rates in eukaryotic cells are associated with genomic instability, resulting in increased numbers of mutational events. In yeast, highly transcribed DNA is now shown to accumulate apurinic/apyrimidinic sites due to the removal of uracil, suggesting that the fidelity of DNA synthesis can be affected by the level of transcription.

    • Nayun Kim
    • Sue Jinks-Robertson
    Research
    Nature
    Volume: 459, P: 1150-1153

  • Drosophila haemocytes collaborate with the tracheal system to reserve and transport oxygen through the phase transition of PPO2 crystals, facilitating internal oxygen homeostasis in a process that is comparable to vertebrate respiration.

    • Mingyu Shin
    • Eunji Chang
    • Jiwon Shim
    ResearchOpen Access
    Nature
    Volume: 631, P: 350-359

  • Transcription poses a risk to the genome through transcription-associated mutagenesis and recombination. This Review discusses recent findings about influences on this genomic instability, such as the rate and direction of transcription or nucleic acid structures, and how these phenomena may be considered across species.

    • Nayun Kim
    • Sue Jinks-Robertson
    Reviews
    Nature Reviews Genetics
    Volume: 13, P: 204-214