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Showing 1–2 of 2 results
Advanced filters: Author: Neeti Ananthaswamy Clear advanced filters

  • Safe delivery of genes is needed for gene therapy. Here the authors build “artificial viral vectors” (AVVs) by engineering the well-characterised structural components of bacteriophage T4: the large capacity, all-in-one, multiplex, programmable, and phage-based AVV nanomaterials have potential for gene therapy.

    • Jingen Zhu
    • Himanshu Batra
    • Venigalla B. Rao
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-19

  • Here, the authors present the structure of the HIV envelope (Env) protein from a transmitted founder virus and show that, while the overall structure of the Env trimer is similar to other closed trimers, the fusion peptide is buried in the hydrophobic core of the trimer, which is similar to open state trimers.

    • Neeti Ananthaswamy
    • Qianglin Fang
    • Venigalla B. Rao
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-10