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Showing 1–4 of 4 results

Advanced filters: Author: Nerges Winblad Clear advanced filters

Erratum: Multiplex gene editing by CRISPR–Cpf1 using a single crRNA array

Bernd Zetsche
Matthias Heidenreich
Feng Zhang
Amendments and Corrections08 Feb 2017
Nature Biotechnology

Volume: 35, P: 178
Polycomb repressive complex 2 shields naïve human pluripotent cells from trophectoderm differentiation

Two side-by-side papers report that H3K27me3 deposited by polycomb repressive complex 2 represents an epigenetic barrier that restricts naïve human pluripotent cell differentiation into alternative lineages including trophoblasts.

Banushree Kumar
Carmen Navarro
Simon J. Elsässer
ResearchOpen Access30 May 2022
Nature Cell Biology

Volume: 24, P: 845-857
At the heart of gene edits in human embryos

The gene-editing technology CRISPR–Cas has been used in human embryos grown in vitro to correct a disease-associated mutation. The introduction of editing components at fertilization aided repair efficiency. See Article p.413

Nerges Winblad
Fredrik Lanner
News & Views02 Aug 2017
Nature

Volume: 548, P: 398-400
Multiplex gene editing by CRISPR–Cpf1 using a single crRNA array

Multiplexed genome editing is simplified by harnessing the ability of Cpf1 to process its own pre-crRNA.

Bernd Zetsche
Matthias Heidenreich
Feng Zhang
Research05 Dec 2016
Nature Biotechnology

Volume: 35, P: 31-34