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Showing 1–4 of 4 results

Advanced filters: Author: Nianchao Qian Clear advanced filters

Volumetric DNA microscopy for mapping spatial transcriptomes in three dimensions

This protocol for encoding spatial information via DNA sequences enables template-free reconstruction of three-dimensional gene expression patterns in intact specimens, thereby overcoming the limitations of two-dimensional spatial imaging.

Nianchao Qian
Jing Li
Joshua A. Weinstein
Protocols24 Feb 2026
Nature Protocols

P: 1-40
Gain-of-function genetic screening identifies the antiviral function of TMEM120A via STING activation

Understanding the interplay between host and viral factors during infection is essential for the interactome of infection. Here the authors perform a gain-of-function screen to identify factors involved during Zika virus infection and identify TMEM120A as a key factor in the STING mediated immune responses.

Shuo Li
Nianchao Qian
Xu Tan
ResearchOpen Access10 Jan 2022
Nature Communications

Volume: 13, P: 1-12
Spatial transcriptomic imaging of an intact organism using volumetric DNA microscopy

Volumetric DNA microscopy captures spatial information of RNA within an intact organism.

Nianchao Qian
Joshua A. Weinstein
ResearchOpen Access27 Mar 2025
Nature Biotechnology

Volume: 44, P: 222-232
Structure of the African swine fever virus major capsid protein p72

Qi Liu
Bingting Ma
Ye Xiang
CorrespondenceOpen Access17 Sept 2019
Cell Research

Volume: 29, P: 953-955

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