Oral biofilms are the paradigm of multispecies biofilms. Paul Kolenbrander and colleagues describe the different steps in the formation of these biofilms, the importance of intercellular cooperation and signalling, and how this can lead to pathogenesis. In all these aspects, the distance between the bacteria is an important factor.
- Paul E. Kolenbrander
- Robert J. Palmer Jr
- Nicholas S. Jakubovics
