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Showing 1–2 of 2 results
Advanced filters: Author: Nick Van Reet Clear advanced filters

  • African trypanosomes can reduce their requirement for tsetse fly transmission, allowing an expanded geographical range. Here, molecular analyses of field and laboratory selected lines has identified adaptions for the parasite’s simplified life cycle.

    • Guy R. Oldrieve
    • Frank Venter
    • Keith R. Matthews
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-14

  • Recombinant proteins based on APOL1 and APOL3 can kill pathogenic Trypanosoma brucei subspecies, including a variant (rPpMUT) that is effective against T.b. gambiense infection in mice, suggesting that it may serve as a therapy against sleeping sickness.

    • Frédéric Fontaine
    • Laurence Lecordier
    • Etienne Pays
    Research
    Nature Microbiology
    Volume: 2, P: 1500-1506