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Showing 51–100 of 527 results
Advanced filters: Author: Nicola McCarthy Clear advanced filters

    • Nicola McCarthy
    Research Highlights
    Nature Reviews Cancer
    Volume: 8, P: 741

  • Post-international travel quarantine has been widely implemented to mitigate SARS-CoV-2 transmission, but the impacts of such policies are unclear. Here, the authors used linked genomic and contact tracing data to assess the impacts of a 14-day quarantine on return to England in summer 2020.

    • Dinesh Aggarwal
    • Andrew J. Page
    • Ewan M. Harrison
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-13

  • In this study, Aggarwal and colleagues perform prospective sequencing of SARS-CoV-2 isolates derived from asymptomatic student screening and symptomatic testing of students and staff at the University of Cambridge. They identify important factors that contributed to within university transmission and onward spread into the wider community.

    • Dinesh Aggarwal
    • Ben Warne
    • Ian G. Goodfellow
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-16

  • A genome-wide association study of critically ill patients with COVID-19 identifies genetic signals that relate to important host antiviral defence mechanisms and mediators of inflammatory organ damage that may be targeted by repurposing drug treatments.

    • Erola Pairo-Castineira
    • Sara Clohisey
    • J. Kenneth Baillie
    Research
    Nature
    Volume: 591, P: 92-98

  • Exome-sequencing analyses of a large cohort of patients with type 2 diabetes and control individuals without diabetes from five ancestries are used to identify gene-level associations of rare variants that are associated with type 2 diabetes.

    • Jason Flannick
    • Josep M. Mercader
    • Michael Boehnke
    ResearchOpen Access
    Nature
    Volume: 570, P: 71-76

  • Several recent reports in the popular press have indicated that the benefits of exposure to sunlight might outweigh the risks of developing skin cancer.

    • Nicola McCarthy
    News
    Nature Reviews Cancer
    Volume: 13, P: 378

  • ThisNaturepaper shows that inhibition of haem oxygenase 1 is synthetic lethal in kidney cells lacking the tumour suppressor fumarate hydratase.

    • Nicola McCarthy
    Research Highlights
    Nature Reviews Cancer
    Volume: 11, P: 693

    • Nicola McCarthy
    News
    Nature Reviews Cancer
    Volume: 5, P: 8

    • Nicola McCarthy
    Research Highlights
    Nature Reviews Cancer
    Volume: 13, P: 379

    • Nicola McCarthy
    Research Highlights
    Nature Reviews Cancer
    Volume: 6, P: 829

    • Nicola McCarthy
    News
    Nature Reviews Cancer
    Volume: 5, P: 584

    • Nicola McCarthy
    Research Highlights
    Nature Reviews Cancer
    Volume: 9, P: 534-535

    • Nicola McCarthy
    Research Highlights
    Nature Reviews Cancer
    Volume: 4, P: 754

    • Nicola McCarthy
    Research Highlights
    Nature Reviews Cancer
    Volume: 13, P: 379

    • Nicola McCarthy
    Research Highlights
    Nature Reviews Cancer
    Volume: 13, P: 8

    • Nicola McCarthy
    Research Highlights
    Nature Reviews Cancer
    Volume: 5, P: 154

    • Nicola McCarthy
    Research Highlights
    Nature Reviews Cancer
    Volume: 4, P: 923

    • Nicola McCarthy
    Research Highlights
    Nature Reviews Cancer
    Volume: 12, P: 374

    • Nicola McCarthy
    Research Highlights
    Nature Reviews Cancer
    Volume: 9, P: 689

  • Three papers show that HiPSCs differ at the genetic and epigenetic levels compared with HESCs.

    • Nicola McCarthy
    Research Highlights
    Nature Reviews Cancer
    Volume: 11, P: 232

  • Findings published by the World Health Organization predict that the number of people diagnosed with cancer each year will be 24 million by 2035.

    • Nicola McCarthy
    News
    Nature Reviews Cancer
    Volume: 14, P: 154

  • This paper shows that misorientation of the spindle poles in dividing epithelial cells can lead to aberrant cell growth in the absence of apoptosis.

    • Nicola McCarthy
    Research Highlights
    Nature Reviews Cancer
    Volume: 13, P: 606-607

    • Nicola McCarthy
    Research Highlights
    Nature Reviews Cancer
    Volume: 14, P: 6

    • Nicola McCarthy
    Research Highlights
    Nature Reviews Cancer
    Volume: 12, P: 81

    • Nicola McCarthy
    Research Highlights
    Nature Reviews Cancer
    Volume: 6, P: 256

    • Nicola McCarthy
    Research Highlights
    Nature Reviews Cancer
    Volume: 5, P: 333

    • Nicola McCarthy
    Research Highlights
    Nature Reviews Cancer
    Volume: 12, P: 511

    • Nicola McCarthy
    Research Highlights
    Nature Reviews Cancer
    Volume: 4, P: 833

    • Nicola McCarthy
    Research Highlights
    Nature Reviews Cancer
    Volume: 8, P: 249

  • Exposure of mouse skin to UVB early in life generates macrophage infiltration and an interferon-γ response that promotes melanocytic survival, evasion of the immune response and oncogenesis.

    • Nicola McCarthy
    Research Highlights
    Nature Reviews Cancer
    Volume: 11, P: 154-155

    • Nicola McCarthy
    Research Highlights
    Nature Reviews Cancer
    Volume: 5, P: 917

  • A paper published inScienceindicates that one of two common histone mutations found in paediatric glioblastoma is a gain-of-function mutation that inhibits histone trimethylation that is mediated by the Polycomb repressive complex 2 (PRC2).

    • Nicola McCarthy
    Research Highlights
    Nature Reviews Cancer
    Volume: 13, P: 294

    • Nicola McCarthy
    Research Highlights
    Nature Reviews Cancer
    Volume: 6, P: 746

    • Nicola McCarthy
    Research Highlights
    Nature Reviews Cancer
    Volume: 9, P: 771

    • Nicola McCarthy
    Research Highlights
    Nature Reviews Cancer
    Volume: 6, P: 658

    • Nicola McCarthy
    Research Highlights
    Nature Reviews Cancer
    Volume: 12, P: 7