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Showing 1–4 of 4 results
Advanced filters: Author: Nicolae Sapoval Clear advanced filters

  • Tiled amplicon sequencing is an essential tool for tracking the spread and evolution of pathogens, including SARS-CoV-2, however existing methods for tiled amplicon design require slow and costly downstream manual optimization. Here the authors present Olivar, a first step towards fully automated, variant-aware design of tiled amplicons for pathogen genomes.

    • Michael X. Wang
    • Esther G. Lou
    • Todd J. Treangen
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-12

  • Wastewater surveillance has the potential to be used for early detection of new SARS-CoV-2 lineages. Here, the authors present Crykey, a computational method for detecting cryptic SARS-CoV-2 mutations in wastewater that co-occur on the same sequencing read, potentially representing new lineages.

    • Yunxi Liu
    • Nicolae Sapoval
    • Lauren B. Stadler
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-13