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Maternal stress triggers early-life eczema through fetal mast cell programming

Prenatal stress triggers molecular dysregulations in fetal neuroimmune circuits, leading to altered mast cell and sensory neuron function, which predisposes offspring to develop eczema in response to otherwise harmless mechanical friction after birth.

Nadine Serhan
Nasser S. Abdullah
Nicolas Gaudenzio
ResearchOpen Access27 Aug 2025
Nature

Volume: 646, P: 161-170
Structure and boosting activity of a starch-degrading lytic polysaccharide monooxygenase

Lytic polysaccharide monooxygenases (LPMOs) are industrially important enzymes that oxidatively deconstruct polysaccharides. Here, Lo Leggio et al. report the activity, spectroscopy and three-dimensional structure of a LPMO of the new CAZy AA13 family active on recalcitrant-retrograded starch.

Leila Lo Leggio
Thomas J. Simmons
Paul H. Walton
ResearchOpen Access22 Jan 2015
Nature Communications

Volume: 6, P: 1-9
Lytic xylan oxidases from wood-decay fungi unlock biomass degradation

A new type of fungal lytic polysaccharide monooxygenase (LPMO) catalyzes the oxidative degradation of xylan components of cellulosic biomass and offers potential in wood biorefining.

Marie Couturier
Simon Ladevèze
Jean-Guy Berrin
Research29 Jan 2018
Nature Chemical Biology

Volume: 14, P: 306-310
The molecular basis of polysaccharide cleavage by lytic polysaccharide monooxygenases

Lytic polysaccharide monooxygenases (LPMOs) are a class of copper-dependent enzymes that oxidatively degrade polysaccharides and find use in industrial processing of lignocellulose. Crystallographic and spectroscopic studies define how LPMOs recognize their oligosaccharide substrates and mediate oxidative cleavage.

Kristian E H Frandsen
Thomas J Simmons
Paul H Walton
Research29 Feb 2016
Nature Chemical Biology

Volume: 12, P: 298-303
Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptor

Céline Lukowicz
Sandrine Ellero-Simatos
Laïla Mselli-Lakhal
ResearchOpen Access27 Dec 2019
Scientific Reports

Volume: 9, P: 1-13
Selective layer-free blood serum ionogram based on ion-specific interactions with a nanotransistor

An ionogram based on a layer-free nanotransistor reveals the ability to selectively measure target ions in serum. Experimental and theoretical assessment of the mechanism of the surface–ion interaction is also revealed.

R. Sivakumarasamy
R. Hartkamp
N. Clément
Research05 Feb 2018
Nature Materials

Volume: 17, P: 464-470
Author Correction: Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptor

Céline Lukowicz
Sandrine Ellero-Simatos
Laïla Mselli-Lakhal
Amendments and CorrectionsOpen Access03 Mar 2020
Scientific Reports

Volume: 10, P: 1-2

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Maternal stress triggers early-life eczema through fetal mast cell programming

Structure and boosting activity of a starch-degrading lytic polysaccharide monooxygenase

Lytic xylan oxidases from wood-decay fungi unlock biomass degradation

The molecular basis of polysaccharide cleavage by lytic polysaccharide monooxygenases

Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptor

Selective layer-free blood serum ionogram based on ion-specific interactions with a nanotransistor

Author Correction: Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptor

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