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Showing 1–5 of 5 results
Advanced filters: Author: Nicole A. Spiegelman Clear advanced filters

  • The spatiotemporal activation of phagocytosis by hair follicle cells is orchestrated by lipids released from surrounding apoptotic cells and retinoids released by healthy cells.

    • Katherine S. Stewart
    • Merve Deniz Abdusselamoglu
    • Elaine Fuchs
    ResearchOpen Access
    Nature
    Volume: 633, P: 407-416

  • Evidence from mice and humans indicates that peripartum cardiomyopathy (PPCM) is a vascular disease caused by excessive anti-angiogenic signalling in the peripartum period of pregnancy and that pre-eclampsia and multiple gestation are important risk factors for the development of PPCM.

    • Ian S. Patten
    • Sarosh Rana
    • Zoltan Arany
    Research
    Nature
    Volume: 485, P: 333-338

  • Here the authors revealed a role for the protein deacetylase SIRT2 in Golgi stress, particularly induced by bacterial infection. Shigella secrete effector proteins such as IcsB, which transfers fatty acyl groups to modify host proteins to evade host immune surveillance. The upregulated SIRT2 counteracts this function by removing the fatty acyl groups and enhancing the killing of Shigella.

    • Miao Wang
    • Yugang Zhang
    • Hening Lin
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-13