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Showing 1–3 of 3 results
Advanced filters: Author: Nicole Caduff Clear advanced filters

  • Kaposi sarcoma associated herpesvirus (KSHV) and Epstein Barr virus often co-infect hosts and some malignancies, such as primary effusion lymphoma, are typically arising from dual-infected cells. Here authors recapitulate dual infection in a humanized mouse model, and find that under these conditions, an efficient and specific CD8+ T cell response is mounted against the lytic KSHV antigen K6.

    • Nicole Caduff
    • Lisa Rieble
    • Christian Münz
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-13

  • The persistence of the immune response to SARS-CoV-2 after recovery from infection is an indicator for subsequent protection against infection. Here the authors follow recovered patients and measure antibody and T cell responses and find that these two parts of the immune response may have different longevity.

    • Dominik Menges
    • Kyra D. Zens
    • Jan S. Fehr
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-16

  • MxB is an interferon-induced GTPase that inhibits HIV replication. Here, Crameri et al. show that MxB restricts replication of herpesviruses by inhibiting delivery of incoming viral DNA into the nucleus, and this antiviral activity depends on MxB’s GTPase activity.

    • Michel Crameri
    • Michael Bauer
    • Jovan Pavlovic
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-16