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Scientific Reports (2)
Communications Biology (1)

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Showing 1–3 of 3 results

Advanced filters: Author: Nicole Schmitner Clear advanced filters

Conserved glucokinase regulation in zebrafish confirms therapeutic utility for pharmacologic modulation in diabetes

A study in zebrafish identifying orthologs of mammalian glucokinase isoforms shows physiological responses to nutrition and disrupted responses under diabetic conditions, which are improved by treatment with the glucokinase activator Dorzagliatin.

Nicole Schmitner
Sophie Thumer
Robin A. Kimmel
ResearchOpen Access23 Nov 2024
Communications Biology

Volume: 7, P: 1-11
Diabetic pdx1-mutant zebrafish show conserved responses to nutrient overload and anti-glycemic treatment

Robin A. Kimmel
Stefan Dobler
Dirk Meyer
ResearchOpen Access18 Sept 2015
Scientific Reports

Volume: 5, P: 1-14
Tcf7l2 plays pleiotropic roles in the control of glucose homeostasis, pancreas morphology, vascularization and regeneration

Nicola Facchinello
Estefania Tarifeño-Saldivia
Francesco Argenton
ResearchOpen Access29 Aug 2017
Scientific Reports

Volume: 7, P: 1-16