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Showing 1–3 of 3 results
Advanced filters: Author: Nina L. Fransen Clear advanced filters

  • Tissue-resident immune cells are important for local protections from pathogens. Here the authors show that brain tissue-resident memory T cells (TRM cells) can be further subsetted by CD103 expression, with higher CD103 correlates with increased chemokine receptor and exhaustion markers such as PD1 or CTLA4, but reduced differentiation markers.

    • Joost Smolders
    • Kirstin M. Heutinck
    • Jörg Hamann
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-14

  • Albena Jordanova and colleagues report mutations in HINT1 in autosomal recessive axonal neuropathy with neuromyotonia. Using linkage analysis and whole-genome sequencing, they identify 8 mutations in 33 affected families.

    • Magdalena Zimoń
    • Jonathan Baets
    • Albena Jordanova
    Research
    Nature Genetics
    Volume: 44, P: 1080-1083

  • Microglia nodules are associated with brain pathology. Here, the authors show demyelination in microglia nodules in multiple sclerosis (MS), likely due to oxidized phospholipid phagocytosis and immune activation, suggesting that nodules could be involved in MS lesion formation.

    • Aletta M. R. van den Bosch
    • Marlijn van der Poel
    • Jörg Hamann
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-16