Establishment of biological sex involves differentiation of the primary gonad, which is biased towards ovarian fates in many species. Here they show that the RNA binding protein Rbpms2 acts as a repressor of “testis” RNAs in oocytes and identify an oocyte progression checkpoint regulated by Rbpms2 and the Gator2 protein, Mios.
- Miranda L. Wilson
- Shannon N. Romano
- Florence L. Marlow
