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Showing 1–11 of 11 results
Advanced filters: Author: Niv Zmora Clear advanced filters

  • Current nutritional approaches to prevent and treat various diseases have limited effectiveness. Here, Zmora et al. review the major principles underlying effects of dietary constituents on the gut microbiota, resolving aspects of the diet–microbiota–host crosstalk, and present the promises and challenges of incorporating microbiome data into dietary planning.

    • Niv Zmora
    • Jotham Suez
    • Eran Elinav
    Reviews
    Nature Reviews Gastroenterology & Hepatology
    Volume: 16, P: 35-56

  • Direct gut sampling shows that probiotics reduce the number of antibiotic resistance genes in the gut of colonization-permissive and antibiotic-naïve individuals. However, when given after antibiotic treatment, probiotics can expand the gut resistome via a bloom of indigenous strains carrying vancomycin resistance genes, rather than antibiotic resistance genes carried by the probiotics themselves.

    • Emmanuel Montassier
    • Rafael Valdés-Mas
    • Eran Elinav
    ResearchOpen Access
    Nature Microbiology
    Volume: 6, P: 1043-1054

  • Statistical analyses of a metagenomics-sequenced human cohort identify a relatively minor role for genetics in determining microbiome composition and show that several human phenotypes are as strongly associated with the gut microbiome as with host genetics.

    • Daphna Rothschild
    • Omer Weissbrod
    • Eran Segal
    Research
    Nature
    Volume: 555, P: 210-215

  • Non-caloric artificial sweeteners (NAS), widely used food additives considered to be safe and beneficial alternatives to sugars, are shown here to lead to the development of glucose intolerance through compositional and functional changes in the gut microbiota of mice, and the deleterious metabolic effects are transferred to germ-free mice by faecal transplant; NAS-induced dysbiosis and glucose intolerance are also demonstrated in healthy human subjects.

    • Jotham Suez
    • Tal Korem
    • Eran Elinav
    Research
    Nature
    Volume: 514, P: 181-186

  • The use and promotion of probiotics is widespread, but debatable in many cases. Prospective large-scale randomized studies that assess their effectiveness in promoting health and curing disease and take into account personalized responses of discrete human subpopulations will help clarify specific indications in which probiotics may be safe and beneficial.

    • Jotham Suez
    • Niv Zmora
    • Eran Elinav
    Reviews
    Nature Medicine
    Volume: 25, P: 716-729

  • Here, the authors describe how metabolic disorders, such as type 2 diabetes and nonalcoholic fatty liver disease, are driven by alterations in the composition of the intestinal microbiota and its metabolites, which translocate from the gut across a disrupted intestinal barrier and contribute to metabolic inflammation.

    • Herbert Tilg
    • Niv Zmora
    • Eran Elinav
    Reviews
    Nature Reviews Immunology
    Volume: 20, P: 40-54