Nature Search

Mitochondrial protein C15ORF48 is a stress-independent inducer of autophagy that regulates oxidative stress and autoimmunity

Stress-independent autophagy is less understood than stress-induced autophagy and is important for thymic self-tolerance. Here the authors show that a mitochondrial protein C15ORF48 is important for stress-independent autophagy and alters glutathione metabolism and C15orf48 knockout mice develop autoimmunity and changes to thymic epithelial cells.

Yuki Takakura
Moeka Machida
Noritaka Yamaguchi
ResearchOpen Access01 Feb 2024
Nature Communications

Volume: 15, P: 1-19
A multi-antigen-based SARS-CoV-2 vaccine provides higher immune responses and protection against SARS-CoV-2 variants

Marwa Alhashimi
Ekramy E. Sayedahmed
Suresh K. Mittal
ResearchOpen Access19 Jul 2025
npj Vaccines

Volume: 10, P: 1-18
Calreticulin and integrin alpha dissociation induces anti-inflammatory programming in animal models of inflammatory bowel disease

Inflammatory bowel disease (IBD) is initiated by integrins-mediated leukocyte adhesion to the activated colonic microvascular endothelium. Here, the authors show that inhibition of the calreticulin binding to integrin α subunits ameliorates the severity of IBD in animal models.

Masayoshi Ohkuro
Jun-Dal Kim
Akiyoshi Fukamizu
ResearchOpen Access17 May 2018
Nature Communications

Volume: 9, P: 1-10
Impact of feline AIM on the susceptibility of cats to renal disease

Ryoichi Sugisawa
Emiri Hiramoto
Toru Miyazaki
ResearchOpen Access12 Oct 2016
Scientific Reports

Volume: 6, P: 1-13
Plasmodium cynomolgi genome sequences provide insight into Plasmodium vivax and the monkey malaria clade

Jane Carlton, Kazuyuki Tanabe and colleagues report the draft genome sequences of three Plasmodium cynomolgi strains isolated from infected monkeys. Their comparative genomic analysis with P. vivax and P. knowlesi offers insights into these simian malaria parasites.

Shin-Ichiro Tachibana
Steven A Sullivan
Kazuyuki Tanabe
ResearchOpen Access05 Aug 2012
Nature Genetics

Volume: 44, P: 1051-1055
Obesity reduces the anticancer effect of AdipoRon against orthotopic pancreatic cancer in diet-induced obese mice

Keizo Takenaga
Miho Akimoto
Hiroki Nagase
ResearchOpen Access03 Feb 2021
Scientific Reports

Volume: 11, P: 1-13
Post-transcriptional regulation of BRG1 by FIRΔexon2 in gastric cancer

Guzhanuer Ailiken
Kouichi Kitamura
Kazuyuki Matsushita
ResearchOpen Access18 Feb 2020
Oncogenesis

Volume: 9, P: 1-20
Down-regulation of GATA1-dependent erythrocyte-related genes in the spleens of mice exposed to a space travel

Kenta Horie
Hiroki Sasanuma
Taishin Akiyama
ResearchOpen Access21 May 2019
Scientific Reports

Volume: 9, P: 1-11
Fatty liver incidence and predictive variables

Akira Tsuneto
Ayumi Hida
Masazumi Akahoshi
Research09 Apr 2010
Hypertension Research

Volume: 33, P: 638-643
Comparative analysis of necrotizing enterocolitis in preterm infants born in Japan and born to mothers of Japanese ethnicity in California

Satoshi Kusuda
Mihoko V. Bennett
Asao Yara
ResearchOpen Access22 Mar 2025
Scientific Reports

Volume: 15, P: 1-11
CD4⁺ T Cell-Mediated Cytotoxicity Toward Thyrocytes: The Importance of Fas/Fas Ligand Interaction Inducing Apoptosis of Thyrocytes and the Inhibitory Effect of Thyroid-Stimulating Hormone

Atsushi Kawakami
Naoki Matsuoka
Katsumi Eguchi
Research01 Apr 2000
Laboratory Investigation

Volume: 80, P: 471-484

Search

Mitochondrial protein C15ORF48 is a stress-independent inducer of autophagy that regulates oxidative stress and autoimmunity

A multi-antigen-based SARS-CoV-2 vaccine provides higher immune responses and protection against SARS-CoV-2 variants

Calreticulin and integrin alpha dissociation induces anti-inflammatory programming in animal models of inflammatory bowel disease

Impact of feline AIM on the susceptibility of cats to renal disease

Plasmodium cynomolgi genome sequences provide insight into Plasmodium vivax and the monkey malaria clade

Obesity reduces the anticancer effect of AdipoRon against orthotopic pancreatic cancer in diet-induced obese mice

Post-transcriptional regulation of BRG1 by FIRΔexon2 in gastric cancer

Down-regulation of GATA1-dependent erythrocyte-related genes in the spleens of mice exposed to a space travel

Fatty liver incidence and predictive variables

Comparative analysis of necrotizing enterocolitis in preterm infants born in Japan and born to mothers of Japanese ethnicity in California

CD4⁺ T Cell-Mediated Cytotoxicity Toward Thyrocytes: The Importance of Fas/Fas Ligand Interaction Inducing Apoptosis of Thyrocytes and the Inhibitory Effect of Thyroid-Stimulating Hormone

Search

Quick links

Search

Filter By:

Search

Quick links