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Advanced filters: Author: Noelia Bernardo-García Clear advanced filters

Crystallographic snapshots of a B₁₂-dependent radical SAM methyltransferase

Structural and spectroscopic studies show how a B₁₂-dependent radical SAM enzyme catalyses unique and challenging alkylation chemistry, including protein post-translational modification required for methane biosynthesis.

Cameron D. Fyfe
Noelia Bernardo-García
Olivier Berteau
ResearchOpen Access02 Feb 2022
Nature

Volume: 602, P: 336-342
Nucleus-translocated mitochondrial cytochrome c liberates nucleophosmin-sequestered ARF tumor suppressor by changing nucleolar liquid–liquid phase separation

The tumor suppressor ARF is retained by nucleophosmin (NPM) in nucleoli, but shifted out upon DNA damage. In this study, the authors show that cytochrome c triggers a conformational change on NPM, driving ARF release and controlling protein trafficking.

Katiuska González-Arzola
Antonio Díaz-Quintana
Irene Díaz-Moreno
Research11 Oct 2022
Nature Structural & Molecular Biology

Volume: 29, P: 1024-1036
Deciphering how Cpl-7 cell wall-binding repeats recognize the bacterial peptidoglycan

Noemí Bustamante
Manuel Iglesias-Bexiga
Margarita Menéndez
ResearchOpen Access28 Nov 2017
Scientific Reports

Volume: 7, P: 1-17

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