Nature Search

Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood

Yaniv Ziv
Noga Ron
Michal Schwartz
Research15 Jan 2006
Nature Neuroscience

Volume: 9, P: 268-275
Bacteriophage therapy against pathological Klebsiella pneumoniae ameliorates the course of primary sclerosing cholangitis

Patients with primary sclerosing cholangitis (PSC) harboring Klebsiella pneumoniae (Kp) exhibit poor clinical outcomes. Here, the authors show that administration of a phage cocktail targeting PSC-derived Kp reduces bacterial burden in Kp-colonized mice and alleviates liver injury.

Masataka Ichikawa
Nobuhiro Nakamoto
Takanori Kanai
ResearchOpen Access05 Jun 2023
Nature Communications

Volume: 14, P: 1-13
Maintenance of CD4 T cell fitness through regulation of Foxo1

Foxo proteins are required for maintaining T cell quiescence. Turka and colleagues use a constitutively active Foxo1 in T_reg cells to show that its downregulation is essential for maintaining their fitness in a competitive environment.

Ryan H. Newton
Sharad Shrestha
Laurence A. Turka
Research09 Jul 2018
Nature Immunology

Volume: 19, P: 838-848
Perturbed myoepithelial cell differentiation in BRCA mutation carriers and in ductal carcinoma in situ

Myoepithelial cells prevent tumour growth and invasion in DCIS. Here, the authors show that p63 and TCF7 cooperate to regulate a transcription factor network for the maintenance of normal myoepithelial function and altered expression of these genes perturb myoepithelial function in DCIS to promote invasive progression.

Lina Ding
Ying Su
Kornelia Polyak
ResearchOpen Access13 Sept 2019
Nature Communications

Volume: 10, P: 1-16
Geographical migration and fitness dynamics of Streptococcus pneumoniae

Mathematical modelling of 15 years of data from South Africa reveals the spread and vaccine-driven changes in fitness and antimicrobial resistance of Streptococcus pneumoniae.

Sophie Belman
Noémie Lefrancq
Henrik Salje
ResearchOpen Access03 Jul 2024
Nature

Volume: 631, P: 386-392
Suppression by T_FR cells leads to durable and selective inhibition of B cell effector function

Follicular regulatory T cells (T_FR cells) inhibit follicular helper T cell (T_FH cell)-mediated antibody production. Sharpe and colleagues show that T_FR cells induce a distinct suppressive state in T_FH cells and B cells that can be reversed by the cytokine IL-21.

Peter T Sage
Noga Ron-Harel
Arlene H Sharpe
Research03 Oct 2016
Nature Immunology

Volume: 17, P: 1436-1446

Search

Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood

Bacteriophage therapy against pathological Klebsiella pneumoniae ameliorates the course of primary sclerosing cholangitis

Maintenance of CD4 T cell fitness through regulation of Foxo1

Perturbed myoepithelial cell differentiation in BRCA mutation carriers and in ductal carcinoma in situ

Geographical migration and fitness dynamics of Streptococcus pneumoniae

Suppression by T_FR cells leads to durable and selective inhibition of B cell effector function

Search

Quick links

Search

Filter By:

Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood

Bacteriophage therapy against pathological Klebsiella pneumoniae ameliorates the course of primary sclerosing cholangitis

Maintenance of CD4 T cell fitness through regulation of Foxo1

Perturbed myoepithelial cell differentiation in BRCA mutation carriers and in ductal carcinoma in situ

Geographical migration and fitness dynamics of Streptococcus pneumoniae

Suppression by TFR cells leads to durable and selective inhibition of B cell effector function

Search

Quick links

Suppression by T_FR cells leads to durable and selective inhibition of B cell effector function