Dysregulation of the natriuretic peptide system has been associated with several life-style related metabolic and cardiovascular disorders, including obesity, type 2 diabetes mellitus, hypertension, atherosclerosis, thrombosis, and myocardial ischaemia, implying biological effects beyond pressure–volume homeostasis. In this Review, Zois et al. discuss the role of the various natriuretic peptides in the pathophysiology of these cardiometabolic conditions.
- Nora E. Zois
- Emil D. Bartels
- Jens P. Goetze
