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Showing 1–10 of 10 results

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Genome-wide association meta-analysis identifies GP2 gene risk variants for pancreatic cancer

Previous genome-wide association studies have identified risk loci for pancreatic cancer but were centered on individuals of European ancestry. Here the authors identify GP2 gene variants associated with pancreatic cancer susceptibility in populations of East Asian ancestry.

Yingsong Lin
Masahiro Nakatochi
Keitaro Matsuo
ResearchOpen Access24 Jun 2020
Nature Communications

Volume: 11, P: 1-12
SIRT7 has a critical role in bone formation by regulating lysine acylation of SP7/Osterix

SP7/Osterix is a transcription factor involved in osteoblast differentiation. Here, the authors show that Sirtuin 7 activates Osterix posttranslationally by regulating its lysine acylation, and that mice lacking Sirtuin 7 in osteoblasts show reduced bone formation.

Masatoshi Fukuda
Tatsuya Yoshizawa
Kazuya Yamagata
ResearchOpen Access19 Jul 2018
Nature Communications

Volume: 9, P: 1-14
IMiDs uniquely synergize with TKIs to upregulate apoptosis of Philadelphia chromosome-positive acute lymphoblastic leukemia cells expressing a dominant-negative IKZF1 isoform

Daisuke Harama
Takashi Yahata
Kanji Sugita
ResearchOpen Access11 Jun 2021
Cell Death Discovery

Volume: 7, P: 1-14
Impact of drainage retinotomy on surgical outcomes of retinal detachment: insights from the Japan-Retinal Detachment Registry

Hisashi Fukuyama
Hiroto Ishikawa
Shin Yamane
ResearchOpen Access02 Apr 2024
Scientific Reports

Volume: 14, P: 1-8
[Scientific Statement]

Takuya Tsuchihashi
Hisashi Kai
Yuhei Kawano
Reviews24 Oct 2013
Hypertension Research

Volume: 36, P: 1026-1031
Green tea and coffee consumption and risk of kidney cancer in Japanese adults

Yichi Chen
Sarah K. Abe
E. Maruyama
ResearchOpen Access24 Nov 2022
Scientific Reports

Volume: 12, P: 1-11
Association between C-reactive protein and risk of overall and 18 site-specific cancers in a Japanese case-cohort

Shiori Suzuki
Ryoko Katagiri
H. Yatsuya
Research10 Feb 2022
British Journal of Cancer

Volume: 126, P: 1481-1489
Effect of surgeon-related factors on outcome of retinal detachment surgery: analyses of data in Japan-retinal detachment registry

Keita Yamakiri
Taiji Sakamoto
Shin Yamane
ResearchOpen Access10 Mar 2022
Scientific Reports

Volume: 12, P: 1-9
Regional and sex differences in retinal detachment surgery: Japan-retinal detachment registry report

Ryoh Funatsu
Hiroto Terasaki
Shin Yamane
ResearchOpen Access18 Oct 2021
Scientific Reports

Volume: 11, P: 1-9
Inflammatory mediator ultra-low-molecular-weight hyaluronan triggers necrosis of B-precursor leukemia cells with high surface CD44 expression

Shin Kasai
Yoshiyuki Furuichi
Kanji Sugita
ResearchOpen Access01 Jun 2017
Cell Death & Disease

Volume: 8, P: e2857