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Showing 1–2 of 2 results
Advanced filters: Author: Nuria Vaquero-Siguero Clear advanced filters
  • Chemotherapy resistance in recurrent gliomas is a large hurdle for successful therapy. Here, the authors show that some recurrent gliomas harbour O-6-methylguanine-DNA methyltransferase (MGMT) genomic rearrangements, and in vitro and in vivo these contribute to temozolomide resistance.

    • Barbara Oldrini
    • Nuria Vaquero-Siguero
    • Massimo Squatrito
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-10
  • The presence of peritoneal metastasis in pancreatic cancers is associated with poor prognosis. Here the authors show that hyaluronan and proteoglycan link protein-1 (HAPLN1) promotes tumour cell plasticity and pro-tumoral immune microenvironment to facilitate peritoneal dissemination in pancreatic cancers.

    • Lena Wiedmann
    • Francesca De Angelis Rigotti
    • Juan Rodriguez-Vita
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-18