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Structural basis for the activation and ligand recognition of the human oxytocin receptor

Here, Waltenspühl et al. report the cryo-EM structure of active human oxytocin receptor in complex with oxytocin and with a heterotrimeric G protein, providing insights into this hormone system critically involved in the regulation of social behaviour and reproduction.

Yann Waltenspühl
Janosch Ehrenmann
Andreas Plückthun
ResearchOpen Access18 Jul 2022
Nature Communications

Volume: 13, P: 1-9
Nonlinear mechanics of lamin filaments and the meshwork topology build an emergent nuclear lamina

Mechanical strength of in situ assembled nuclear lamin filaments arranged in a 3D meshwork is unclear. Here, using mechanical, structural and simulation tools, the authors report the hierarchical organization of the lamin meshwork that imparts strength and toughness to lamin filaments at par with silk and Kevlar^®

K. Tanuj Sapra
Zhao Qin
Ohad Medalia
ResearchOpen Access04 Dec 2020
Nature Communications

Volume: 11, P: 1-14
Slow release of a synthetic auxin induces formation of adventitious roots in recalcitrant woody plants

Adventitious roots are induced in various woody plants, enabling clonal propagation.

Ohad Roth
Sela Yechezkel
Roy Weinstain
Research24 Jan 2024
Nature Biotechnology

Volume: 42, P: 1705-1716
Looking up the sky: unidentified aerial phenomena and macroeconomic attention

Nathan Goldstein
Ohad Raveh
ResearchOpen Access18 Dec 2024
Humanities and Social Sciences Communications

Volume: 11, P: 1-25
A transportome-scale amiRNA-based screen identifies redundant roles of Arabidopsis ABCB6 and ABCB20 in auxin transport

Characterizing plant membrane transporters via genetic methods is complicated by functional redundancy among multi-gene transporter families. Here Zhang et al. use an artificial microRNA-based screen to overcome this issue and show that ABCB6 and ABCB20 act redundantly to regulate auxin transport.

Yuqin Zhang
Victoria Nasser
Eilon Shani
ResearchOpen Access11 Oct 2018
Nature Communications

Volume: 9, P: 1-12

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Structural basis for the activation and ligand recognition of the human oxytocin receptor

Nonlinear mechanics of lamin filaments and the meshwork topology build an emergent nuclear lamina

Slow release of a synthetic auxin induces formation of adventitious roots in recalcitrant woody plants

Looking up the sky: unidentified aerial phenomena and macroeconomic attention

A transportome-scale amiRNA-based screen identifies redundant roles of Arabidopsis ABCB6 and ABCB20 in auxin transport

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