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Showing 1–4 of 4 results

Advanced filters: Author: Oleh Khalimonchuk Clear advanced filters

Coordination of metal center biogenesis in human cytochrome c oxidase

Mitochondrial cytochrome c oxidase is a heme aa3-copper oxygen reductase. Here, authors report that metal center-specific metallochaperones form dynamic assemblies to control heme a biosynthesis and coordinate copper transfer to the copper sites.

Eva Nývltová
Jonathan V. Dietz
Antoni Barrientos
ResearchOpen Access24 Jun 2022
Nature Communications

Volume: 13, P: 1-17
Depletion of mitochondrial protease OMA1 alters proliferative properties and promotes metastatic growth of breast cancer cells

Amita Daverey
Roman M. Levytskyy
Srivatsan Kidambi
ResearchOpen Access14 Oct 2019
Scientific Reports

Volume: 9, P: 1-15
Vitamin B5 metabolism is essential for vacuolar and mitochondrial functions and drug detoxification in fungi

The PCA pathway, essential for synthesizing CoA and AcCoA from vitamin B5, plays a crucial role in fungal cellular processes. Targeting this pathway could enhance antifungal drug efficacy by affecting vacuolar morphology and drug detoxification.

Jae-Yeon Choi
Shalev Gihaz
Choukri Ben Mamoun
ResearchOpen Access23 Jul 2024
Communications Biology

Volume: 7, P: 1-16
Metalloprotease OMA1 Fine-tunes Mitochondrial Bioenergetic Function and Respiratory Supercomplex Stability

Iryna Bohovych
Mario R. Fernandez
Oleh Khalimonchuk
ResearchOpen Access14 Sept 2015
Scientific Reports

Volume: 5, P: 1-14