Nature Search

Langerhans cells lap up HIV-1

Langerhans cells in the skin and mucosa have been thought to mediate the spread of HIV-1 in the body during sexual transmission. Instead, it seems that the cells protect against the virus, a finding with implications for the development of microbicides (pages 367–371).

Olivier Schwartz
News & Views01 Mar 2007
Nature Medicine

Volume: 13, P: 245-246
A new molecular classification to drive precision treatment strategies in primary Sjögren’s syndrome

Sjögren’s syndrome, a disease that primarily affects women, is poorly understood. Here, the authors combine data from a large cohort of patients and healthy controls to identify biomarkers that distinguish patient subgroups to improve our understanding of the disease and facilitate drug development.

Perrine Soret
Christelle Le Dantec
Jacques-Olivier Pers
ResearchOpen Access10 Jun 2021
Nature Communications

Volume: 12, P: 1-18
New insights into the genetic etiology of Alzheimer’s disease and related dementias

Meta-analysis of genome-wide association studies on Alzheimer’s disease and related dementias identifies new loci and enables generation of a new genetic risk score associated with the risk of future Alzheimer’s disease and dementia.

Céline Bellenguez
Fahri Küçükali
Jean-Charles Lambert
ResearchOpen Access04 Apr 2022
Nature Genetics

Volume: 54, P: 412-436
Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

A meta-analysis of genome-wide association studies across different populations highlights new risk loci and provides a genetic risk score that can stratify prostate cancer risk across ancestries.

David V. Conti
Burcu F. Darst
Christopher A. Haiman
Research04 Jan 2021
Nature Genetics

Volume: 53, P: 65-75
Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

A cross-ancestry genome-wide association meta-analysis of amyotrophic lateral sclerosis (ALS) including 29,612 patients with ALS and 122,656 controls identifies 15 risk loci with distinct genetic architectures and neuron-specific biology.

Wouter van Rheenen
Rick A. A. van der Spek
Jan H. Veldink
ResearchOpen Access06 Dec 2021
Nature Genetics

Volume: 53, P: 1636-1648
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

Cecilia Lindgren and colleagues report results of a large-scale genome-wide association study for waist-to-hip ratio, a measure of body fat distribution. They identify 13 new loci associated with this trait, several of which show stronger effects in women than in men.

Iris M Heid
Anne U Jackson
Cecilia M Lindgren
Research10 Oct 2010
Nature Genetics

Volume: 42, P: 949-960
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

Ruth Loos and colleagues report results of a large genome-wide association study for body mass index. They identify 18 new loci associated with this trait, some of which map near key hypothalamic regulators of energy balance.

Elizabeth K Speliotes
Cristen J Willer
Ruth J F Loos
Research10 Oct 2010
Nature Genetics

Volume: 42, P: 937-948
Fibrin-coated collagen fleece versus absorbable dural sealant for sellar closure after transsphenoidal pituitary surgery: a comparative study

Julien Spitaels
Justin Moore
Olivier De Witte
ResearchOpen Access14 May 2022
Scientific Reports

Volume: 12, P: 1-8
Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants

A multi-ancestry genome-wide association study of prostate cancer performed in 156,319 cases and 788,443 controls identifies 187 novel risk variants associated with the disease. Genetic risk scores associated with overall risk, and risk of aggressive disease in men of African ancestry.

Anqi Wang
Jiayi Shen
Christopher A. Haiman
Research09 Nov 2023
Nature Genetics

Volume: 55, P: 2065-2074
A deep catalogue of protein-coding variation in 983,578 individuals

A dataset of coding variation, derived from exome sequencing of nearly one million individuals from a range of ancestries, provides insight into rare variants and could accelerate the discovery of disease-associated genes and advance precision medicine efforts.

Kathie Y. Sun
Xiaodong Bai
Suganthi Balasubramanian
ResearchOpen Access20 May 2024
Nature

Volume: 631, P: 583-592
Two susceptibility loci identified for prostate cancer aggressiveness

Prostate cancer often does not progress to invasive disease and thus markers predicting the course of the disease progression are critical for optimal treatment choices. Here the authors show that variants at two genetic loci correlate with the aggressiveness of prostate cancer.

Sonja I. Berndt
Zhaoming Wang
Stephen J. Chanock
Research05 May 2015
Nature Communications

Volume: 6, P: 1-7
The TEL gene products: nuclear phosphoproteins with DNA binding properties

Hélène Poirel
Cécile Oury
Olivier A Bernard
Research23 Jan 1997
Oncogene

Volume: 14, P: 349-357
Analysis of TEL proteins in human leukemias

Hélène Poirel
Virginie Lacronique
Olivier A Bernard
Research09 Jun 1998
Oncogene

Volume: 16, P: 2895-2903
Publisher Correction: Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

David V. Conti
Burcu F. Darst
Christopher A. Haiman
Amendments and Corrections20 Jan 2021
Nature Genetics

Volume: 53, P: 413
Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm

Solveig Gretarsdottir, Kari Stefansson and colleagues report a genome-wide association study for abdominal aortic aneurysm. They identified a variant located within the DAB2IP gene on 9q33 associated with risk of developing abdominal aortic aneurysm.

Solveig Gretarsdottir
Annette F Baas
Kari Stefansson
Research11 Jul 2010
Nature Genetics

Volume: 42, P: 692-697
Diagnostic impact of DNA methylation classification in adult and pediatric CNS tumors

Laetitia Lebrun
Nathalie Gilis
Isabelle Salmon
ResearchOpen Access22 Jan 2025
Scientific Reports

Volume: 15, P: 1-14
Integrative epigenomics in Sjögren´s syndrome reveals novel pathways and a strong interaction between the HLA, autoantibodies and the interferon signature

María Teruel
Guillermo Barturen
Marta E. Alarcón-Riquelme
ResearchOpen Access02 Dec 2021
Scientific Reports

Volume: 11, P: 1-18
Author Correction: Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

Wouter van Rheenen
Rick A. A. van der Spek
Jan H. Veldink
Amendments and CorrectionsOpen Access31 Jan 2022
Nature Genetics

Volume: 54, P: 361
Genetic evidence of assortative mating in humans

Using whole-genome data for single-nucleotide polymorphism and results from genome-wide association studies, the authors show that people’s preference for pairing with those with similar phenotypic traits has genetic causes and consequences.

Matthew R. Robinson
Aaron Kleinman
Peter M. Visscher
Research09 Jan 2017
Nature Human Behaviour

Volume: 1, P: 1-13
Author Correction: A deep catalogue of protein-coding variation in 983,578 individuals

Kathie Y. Sun
Xiaodong Bai
Suganthi Balasubramanian
Amendments and CorrectionsOpen Access08 Jan 2025
Nature

Volume: 637, P: E26
Complement component C4 structural variation and quantitative traits contribute to sex-biased vulnerability in systemic sclerosis

Martin Kerick
Marialbert Acosta-Herrera
Javier Martin
ResearchOpen Access05 Oct 2022
npj Genomic Medicine

Volume: 7, P: 1-12
Standardization procedure for flow cytometry data harmonization in prospective multicenter studies

Lucas Le Lann
Pierre-Emmanuel Jouve
Michael Zauner
ResearchOpen Access14 Jul 2020
Scientific Reports

Volume: 10, P: 1-8
Molecular subtypes explain lupus epigenomic heterogeneity unveiling new regulatory genetic risk variants

Olivia Castellini-Pérez
Elena Povedano
Marta E. Alarcón-Riquelme
ResearchOpen Access16 Jul 2024
npj Genomic Medicine

Volume: 9, P: 1-13
ERF mutations reveal a balance of ETS factors controlling prostate oncogenesis

In prostate cancer, the oncogenicity of transcription factor ERG is mediated, in part, by competition with another member of the ETS family, ERF.

Rohit Bose
Wouter R. Karthaus
Charles L. Sawyers
Research14 Jun 2017
Nature

Volume: 546, P: 671-675
Mosaic parental germline mutations causing recurrent forms of malformations of cortical development

Julia Lauer Zillhardt
Karine Poirier
Jamel Chelly
Research23 Sept 2015
European Journal of Human Genetics

Volume: 24, P: 611-614
IgM antibodies against malondialdehyde and phosphorylcholine in different systemic rheumatic diseases

Divya Thiagarajan
Nina Oparina
Johan Frostegård
ResearchOpen Access03 Jul 2020
Scientific Reports

Volume: 10, P: 1-13

Search

Langerhans cells lap up HIV-1

A new molecular classification to drive precision treatment strategies in primary Sjögren’s syndrome

New insights into the genetic etiology of Alzheimer’s disease and related dementias

Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

Fibrin-coated collagen fleece versus absorbable dural sealant for sellar closure after transsphenoidal pituitary surgery: a comparative study

Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants

A deep catalogue of protein-coding variation in 983,578 individuals

Two susceptibility loci identified for prostate cancer aggressiveness

The TEL gene products: nuclear phosphoproteins with DNA binding properties

Analysis of TEL proteins in human leukemias

Publisher Correction: Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm

Diagnostic impact of DNA methylation classification in adult and pediatric CNS tumors

Integrative epigenomics in Sjögren´s syndrome reveals novel pathways and a strong interaction between the HLA, autoantibodies and the interferon signature

Author Correction: Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

Genetic evidence of assortative mating in humans

Author Correction: A deep catalogue of protein-coding variation in 983,578 individuals

Complement component C4 structural variation and quantitative traits contribute to sex-biased vulnerability in systemic sclerosis

Standardization procedure for flow cytometry data harmonization in prospective multicenter studies

Molecular subtypes explain lupus epigenomic heterogeneity unveiling new regulatory genetic risk variants

ERF mutations reveal a balance of ETS factors controlling prostate oncogenesis

Mosaic parental germline mutations causing recurrent forms of malformations of cortical development

IgM antibodies against malondialdehyde and phosphorylcholine in different systemic rheumatic diseases

Search

Quick links

Search

Filter By:

Search

Quick links