Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–5 of 5 results
Advanced filters: Author: Omer Schwartzman Clear advanced filters
  • A new approach based on machine-learning integration of 2.1 billion lab measurements of 92 different lab tests from 2.8 million adults, over a span of 18 years, produces models that can stratify one’s risk of having a future abnormal lab test level and subsequent emerging disease.

    • Netta Mendelson Cohen
    • Omer Schwartzman
    • Amos Tanay
    Research
    Nature Medicine
    Volume: 27, P: 1582-1591
  • Here the authors show that DNMT3A and DNMT3B are differentially regulated during endoderm and mesoderm differentiation in mouse development and characterize the dynamic DNMT3A and DNMT3B sequence specificity during gastrulation.

    • Zohar Mukamel
    • Aviezer Lifshitz
    • Amos Tanay
    Research
    Nature Structural & Molecular Biology
    Volume: 29, P: 1252-1265
  • UMI-4C is a rapid, simplified barcoding approach to targeted chromatin conformation capture that produces high-complexity libraries from low sample input, is easily multiplexed and gives a quantitative, statistically defined readout.

    • Omer Schwartzman
    • Zohar Mukamel
    • Amos Tanay
    Research
    Nature Methods
    Volume: 13, P: 685-691
  • Various methodologies have been developed to characterize diverse features of chromatin, but understanding how epigenomic states contribute to cellular heterogeneity requires adoption of these techniques at the single-cell level. This article discusses the technological developments driving single-cell epigenomics, including the practical and bioinformatic challenges and emerging biological insights.

    • Omer Schwartzman
    • Amos Tanay
    Reviews
    Nature Reviews Genetics
    Volume: 16, P: 716-726
  • A conformation capture sequencing method is developed to link multiple genomic loci into three-dimensional proximity chains called chromosomal walks (C-walks), adding to our understanding of how higher-order chromosomal structures participate in genome regulation.

    • Pedro Olivares-Chauvet
    • Zohar Mukamel
    • Amos Tanay
    Research
    Nature
    Volume: 540, P: 296-300