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Showing 1–5 of 5 results
Advanced filters: Author: Oscar A. Nyangiri Clear advanced filters
  • Whole-genome sequencing analyses of African populations provide insights into continental migration, gene flow and the response to human disease, highlighting the importance of including diverse populations in genomic analyses to understand human ancestry and improve health.

    • Ananyo Choudhury
    • Shaun Aron
    • Neil A. Hanchard
    Research
    Nature
    Volume: 586, P: 741-748
  • Sixty years ago it was suggested that the sickle cell disease mutation survives because the heterozygous genotype confers resistance to malaria, resulting in correlation of the two geographical distributions. The authors use a new global assembly of sickle allele frequencies to support this hypothesis at the global scale.

    • Frédéric B. Piel
    • Anand P. Patil
    • Simon I. Hay
    ResearchOpen Access
    Nature Communications
    Volume: 1, P: 1-7
  • The global prevalence of the Duffy blood group variants is important due to the resistance that the Duffy-negative phenotype generally confers uponPlasmodium vivax infection. Hay et al.generate global frequency maps of the common Duffy alleles to show transmission patterns of the malaria parasite.

    • Rosalind E. Howes
    • Anand P. Patil
    • Simon I. Hay
    ResearchOpen Access
    Nature Communications
    Volume: 2, P: 1-10