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Showing 1–9 of 9 results
Advanced filters: Author: Oscar J Abilez Clear advanced filters

  • Technologies to isolate colonies of human pluripotent stem cells from other cell types in a high-throughput manner are lacking. A microfluidic-based approach that exploits differences in the adhesion strength between these cells and a substrate may soon fill the gap.

    • Oscar J. Abilez
    • Joseph C. Wu
    News & Views
    Nature Materials
    Volume: 12, P: 474-476

  • Biophysical factors in an optimized three-dimensional microenvironment enhance the reprogramming efficiency of human somatic cells into pluripotent stem cells when compared to traditional cell-culture substrates.

    • Oscar J. Abilez
    • Joseph C. Wu
    News & Views
    Nature Materials
    Volume: 15, P: 259-261

  • By exploiting the thermoreversible properties of the US Food and Drug Administration–approved poloxamer 407 (triblock polymer) and 2-octylcyanoacrylate bioadhesive, Edward Chang et al. have developed a new method of sutureless vascular anastomosis, even in vessels with a diameter of less than 1.0 mm. This nonmechanical, sutureless approach compared favorably to the standard hand-sewn approach in long-term (two-year) rat studies.

    • Edward I Chang
    • Michael G Galvez
    • Geoffrey C Gurtner
    Research
    Nature Medicine
    Volume: 17, P: 1147-1152

  • A simple, robust, chemically defined method for generating cardiomyocytes from human pluripotent stem cells is described. It should enable the identification of conditions for maturation of these cells.

    • Paul W Burridge
    • Elena Matsa
    • Joseph C Wu
    Research
    Nature Methods
    Volume: 11, P: 855-860

  • Karina Nakayama et al. bioengineer endothelialized mouse skeletal muscle using parallel-aligned nanofibrillar scaffolds. They find that muscle produced using the aligned scaffolds developed a spatially patterned structure and showed improved endothelial interaction compared to muscle engineered with randomly-oriented scaffolds.

    • Karina H. Nakayama
    • Marco Quarta
    • Ngan F. Huang
    ResearchOpen Access
    Communications Biology
    Volume: 2, P: 1-16

  • In this Comment, Ngan Huang et al. discuss recent advances in cardiovascular tissue engineering and some of the main challenges that remain in translating these advances to the clinic. The authors propose future direction for the field to focus research efforts.

    • Ngan F. Huang
    • Vahid Serpooshan
    • Joseph C. Wu
    Comments & OpinionOpen Access
    Communications Biology
    Volume: 1, P: 1-4