Mutations in daf-2/insulin/IGF-1 receptor impair the growth and reproduction of C. elegans but conversely enhance immunity and lifespan. Here, the authors show that a missense mutation in the gene retains the effects on lifespan and immunity and improves motility.
- Hae-Eun H. Park
- Wooseon Hwang
- Seung-Jae V. Lee
