Nature Search

Developmental changes in methylation of spermatogenesis–specific genes include reprogramming in the epididymis

Mira Ariel
Howard Cedar
John McCarrey
Research01 May 1994
Nature Genetics

Volume: 7, P: 59-63
Small critical RNAs in the scrapie agent

Steve Simoneau
Marie-Madeleine Ruchoux
Jean-Guy Fournier
ResearchOpen Access16 Jun 2009
Nature Precedings

P: 1
CpNpG methylation in mammalian cells

Susan J. Clark
Janet Harrison
Marianne Frommer
Research01 May 1995
Nature Genetics

Volume: 10, P: 20-27
Liver X receptor unlinks intestinal regeneration and tumorigenesis

Liver X receptor drives epithelial Areg-mediated intestinal regeneration, while preventing tumour growth through adaptive immune responses.

Srustidhar Das
S. Martina Parigi
Eduardo J. Villablanca
ResearchOpen Access20 Nov 2024
Nature

Volume: 637, P: 1198-1206
Sugar phosphate activation of the stress sensor eIF2B

The activity of translation initiation factor eIF2B is known to be modulated through stress-responsive phosphorylation of its substrate eIF2. Here, the authors uncover the regulation of eIF2B by the binding of sugar phosphates, suggesting a link between nutrient status and the rate of protein synthesis.

Qi Hao
Jin-Mi Heo
Carmela Sidrauski
ResearchOpen Access08 Jun 2021
Nature Communications

Volume: 12, P: 1-12
Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 cause Aicardi-Goutières syndrome at the AGS1 locus

Yanick J Crow
Bruce E Hayward
Tomas Lindahl
Research16 Jul 2006
Nature Genetics

Volume: 38, P: 917-920
Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutières syndrome and mimic congenital viral brain infection

Yanick J Crow
Andrea Leitch
Andrew P Jackson
Research16 Jul 2006
Nature Genetics

Volume: 38, P: 910-916
Low Prevalence of Autoantibodies to the Insulin-like Growth Factor I Receptor in Children with Short Stature

Kathleen Thompson
David P Dempsher
Sherida E Tollefsen
Research01 Oct 1992
Pediatric Research

Volume: 32, P: 455-459
Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response

Aicardi-Goutieres syndrome is a genetically determined encephalopathy that is associated with an increased production of interferon alpha, which in turn is central to the pathogenesis of systemic lupus erythematosus. Yanick Crow and colleagues now identify homozygous mutations in an interferon-inducible nuclear gene encoding SAMHD1 in AGS-affected individuals across several pedigrees and characterize its function in modulating an innate immune response.

Gillian I Rice
Jacquelyn Bond
Yanick J Crow
Research14 Jun 2009
Nature Genetics

Volume: 41, P: 829-832
Progressive multifocal leucoencephalopathy with peripheral demyelinating neuropathy after autologous bone marrow transplantation for acute myeloblastic leukemia (FAB5)

P Coppo
JPh Laporte
A Najman
Research12 Feb 1999
Bone Marrow Transplantation

Volume: 23, P: 401-403
212 PERSISTENT PULMONARY VASOCONSTRICTION AFTER POSITIVE END-EXPIRATORY PRESSURE

Deborah L Smith-Wright
Michael F Sweeney
Bradley P Fuhrman
Research01 Apr 1985
Pediatric Research

Volume: 19, P: 146
Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature

Yanick Crow and colleagues show that mutations in ADAR1 cause the autoimmune disorder Aicardi-Goutières syndrome, accompanied by upregulation of interferon-stimulated genes. ADAR1 encodes an enzyme that catalyzes the deamination of adeonosine to inosine in double-stranded RNA, and the findings suggest a possible role for RNA editing in limiting the accumulation of repeat-derived RNA species.

Gillian I Rice
Paul R Kasher
Yanick J Crow
Research23 Sept 2012
Nature Genetics

Volume: 44, P: 1243-1248
Yeast-based directed-evolution for high-throughput structural stabilization of G protein-coupled receptors (GPCRs)

M. Meltzer
T. Zvagelsky
Stanislav Engel
ResearchOpen Access23 May 2022
Scientific Reports

Volume: 12, P: 1-14
Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling

Yanick Crow, Sun Hur and colleagues show that gain-of-function mutations in IFIH1 cause a spectrum of neural and immunological phenotypes associated with enhanced interferon signaling. The mutations increase the affinity of IFIH1 for RNA, leading to immune upregulation and inflammatory disease.

Gillian I Rice
Yoandris del Toro Duany
Yanick J Crow
Research30 Mar 2014
Nature Genetics

Volume: 46, P: 503-509
Persistence of pre-leukemic clones during first remission and risk of relapse in acute myeloid leukemia

M Rothenberg-Thurley
S Amler
K H Metzeler
ResearchOpen Access18 Dec 2017
Leukemia

P: 1-27
Low immunogenicity of seasonal trivalent influenza vaccine among patients receiving docetaxel for a solid tumour: results of a prospective pilot study

P Loulergue
J Alexandre
O Launay
ResearchOpen Access03 May 2011
British Journal of Cancer

Volume: 104, P: 1670-1674
860 Underestimation of Influenza Viral Infection in Childhood Asthma Exacerbations

A Mandelcwajg
F Moulin
D Gendrel
Research01 Nov 2010
Pediatric Research

Volume: 68, P: 431
Effects of eight neuropsychiatric copy number variants on human brain structure

Claudia Modenato
Kuldeep Kumar
Sébastien Jacquemont
ResearchOpen Access20 Jul 2021
Translational Psychiatry

Volume: 11, P: 1-10
Exposure history determines pteropod vulnerability to ocean acidification along the US West Coast

N. Bednaršek
R. A. Feely
H. O. Pörtner
ResearchOpen Access03 Jul 2017
Scientific Reports

Volume: 7, P: 1-12
Single-stranded RNA viruses inactivate the transcriptional activity of p53 but induce NOXA-dependent apoptosis via post-translational modifications of IRF-1, IRF-3 and CREB

C Lallemand
B Blanchard
M G Tovey
Research10 Jul 2006
Oncogene

Volume: 26, P: 328-338

Search

Developmental changes in methylation of spermatogenesis–specific genes include reprogramming in the epididymis

Small critical RNAs in the scrapie agent

CpNpG methylation in mammalian cells

Liver X receptor unlinks intestinal regeneration and tumorigenesis

Sugar phosphate activation of the stress sensor eIF2B

Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 cause Aicardi-Goutières syndrome at the AGS1 locus

Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutières syndrome and mimic congenital viral brain infection

Low Prevalence of Autoantibodies to the Insulin-like Growth Factor I Receptor in Children with Short Stature

Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response

Progressive multifocal leucoencephalopathy with peripheral demyelinating neuropathy after autologous bone marrow transplantation for acute myeloblastic leukemia (FAB5)

212 PERSISTENT PULMONARY VASOCONSTRICTION AFTER POSITIVE END-EXPIRATORY PRESSURE

Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature

Yeast-based directed-evolution for high-throughput structural stabilization of G protein-coupled receptors (GPCRs)

Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling

Persistence of pre-leukemic clones during first remission and risk of relapse in acute myeloid leukemia

Low immunogenicity of seasonal trivalent influenza vaccine among patients receiving docetaxel for a solid tumour: results of a prospective pilot study

860 Underestimation of Influenza Viral Infection in Childhood Asthma Exacerbations

Effects of eight neuropsychiatric copy number variants on human brain structure

Exposure history determines pteropod vulnerability to ocean acidification along the US West Coast

Single-stranded RNA viruses inactivate the transcriptional activity of p53 but induce NOXA-dependent apoptosis via post-translational modifications of IRF-1, IRF-3 and CREB

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