Nature Search

Forecasting Locust Outbreaks

D. L. GUNN
P. M. SYMMONS
Research31 Oct 1959
Nature

Volume: 184, P: 1425-1426
LHRH agonists and human breast cancer cells

G. WILDING
M. CHEN
E. P. GELMANN
Research29 Oct 1987
Nature

Volume: 329, P: 770
Human polynucleotide phosphorylase (hPNPase^old-35): an evolutionary conserved gene with an expanding repertoire of RNA degradation functions

S K Das
S K Bhutia
P B Fisher
Reviews13 Dec 2010
Oncogene

Volume: 30, P: 1733-1743
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

Paul R Burton
David G Clayton
Matthew A Brown
Research21 Oct 2007
Nature Genetics

Volume: 39, P: 1329-1337
Epidemiology of CVD in rheumatic disease, with a focus on RA and SLE

Traditional cardiovascular risk factors combine, in the context of inflammatory rheumatic diseases, with disease-related and treatment-related risk factors, to determine a patient's overall risk of cardiovascular disease (CVD). These competing risks are explored in this Review, which summarizes why CVD risk is increased in these patients, and what remains to understand before patients can be offered the best advice about CVD risk management.

Deborah P. M. Symmons
Sherine E. Gabriel
Reviews31 May 2011
Nature Reviews Rheumatology

Volume: 7, P: 399-408
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

An exciting genome-wide association study in the British population for seven common diseases. This analysis confirms previously identified loci and provides strong evidence for many novel disease susceptibility loci.

Paul R. Burton
David G. Clayton
Jane Worthington
Research07 Jun 2007
Nature

Volume: 447, P: 661-678
CARD9 negatively regulates NLRP3-induced IL-1β production on Salmonella infection of macrophages

IL-1β is important for control of bacterial infections, but when deregulated can lead to excessive inflammation. The authors show that the adaptor protein CARD9 suppresses levels of IL-1β and is downregulated during S. Typhimuriuminfection, thus facilitating an inflammatory response

Milton Pereira
Panagiotis Tourlomousis
Clare E. Bryant
ResearchOpen Access27 Sept 2016
Nature Communications

Volume: 7, P: 1-13
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

Copy number variants (CNVs) account for a major proportion of human genetic diversity and may contribute to genetic susceptibility to disease. Here, a large, genome-wide study of association between common CNVs and eight common human diseases is presented. The study provides a wealth of technical insights that will inform future study design and analysis. The results also indicate that common CNVs that can be 'typed' on existing platforms are unlikely to contribute much to the genetic basis of common diseases.

Nick Craddock
Matthew E. Hurles
Peter Donnelly
Research01 Apr 2010
Nature

Volume: 464, P: 713-720
Epidemiology research in rheumatology—progress and pitfalls

Epidemiological research—the study of the distribution and determinants of disease in populations—relies on knowledge of different data sources, solid study designs and the accurate interpretation of study results. Understanding the methodology of population and clinical epidemiology studies is vital for the study of the distribution and determinants of outcomes in patients with rheumatic diseases.

Deborah P. M. Symmons
Reviews07 Jul 2015
Nature Reviews Rheumatology

Volume: 11, P: 631-638
Erratum: The RA-MAP Consortium: a working model for academia–industry collaboration

Andrew P. Cope
Michael R. Barnes
James Butler
Amendments and Corrections24 Jan 2018
Nature Reviews Rheumatology

Volume: 14, P: 119
Disc degeneration of the lumbar spine in relation to overweight

M Liuke
S Solovieva
H Riihimäki
Research17 May 2005
International Journal of Obesity

Volume: 29, P: 903-908
Specific interaction between genotype, smoking and autoimmunity to citrullinated α-enolase in the etiology of rheumatoid arthritis

Karin Lundberg and colleagues explore gene-gene and gene-environment interactions in susceptibility to rheumatoid arthritis, reporting an association of HLA-DRB1, PTPN22 and smoking stratified by the autoantigen CEP-1.

Hiba Mahdi
Benjamin A Fisher
Karin Lundberg
Research08 Nov 2009
Nature Genetics

Volume: 41, P: 1319-1324
Identification of rare disease genes as drivers of common diseases through tissue-specific gene regulatory networks

Olivier B. Bakker
Annique Claringbould
Patrick Deelen
ResearchOpen Access04 Dec 2024
Scientific Reports

Volume: 14, P: 1-13
Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A

New methods and larger sample groups are used to precisely determine the alleles in the HLA complex which contribute susceptibility to type 1 diabetes.

Sergey Nejentsev
Joanna M. M. Howson
Jane Worthington
Research14 Nov 2007
Nature

Volume: 450, P: 887-892
The RA-MAP Consortium: a working model for academia–industry collaboration

Large partnerships between academia and industry are emerging as a possible solution to the problems surrounding stratified medicine. In this Perspectives article, the members of the RA-MAP Consortium reflect on the challenges and benefits of working in such a partnership.

Andrew P. Cope
Michael R. Barnes
James Butler
Comments & Opinion07 Dec 2017
Nature Reviews Rheumatology

Volume: 14, P: 53-60
Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data

Alberto Romagnoni
Simon Jégou
Pamela Whittaker
ResearchOpen Access17 Jul 2019
Scientific Reports

Volume: 9, P: 1-18
Oral Anti-Tumour Necrosis Factor Domain Antibody V565 Provides High Intestinal Concentrations, and Reduces Markers of Inflammation in Ulcerative Colitis Patients

Suhail Nurbhai
Kevin J. Roberts
J. Scott Crowe
ResearchOpen Access01 Oct 2019
Scientific Reports

Volume: 9, P: 1-12
RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients

John D. Isaacs
Sarah Brockbank
Simon Read
ResearchOpen Access09 May 2022
Scientific Data

Volume: 9, P: 1-13

Search

Forecasting Locust Outbreaks

LHRH agonists and human breast cancer cells

Human polynucleotide phosphorylase (hPNPase^old-35): an evolutionary conserved gene with an expanding repertoire of RNA degradation functions

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

Epidemiology of CVD in rheumatic disease, with a focus on RA and SLE

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

CARD9 negatively regulates NLRP3-induced IL-1β production on Salmonella infection of macrophages

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

Epidemiology research in rheumatology—progress and pitfalls

Erratum: The RA-MAP Consortium: a working model for academia–industry collaboration

Disc degeneration of the lumbar spine in relation to overweight

Specific interaction between genotype, smoking and autoimmunity to citrullinated α-enolase in the etiology of rheumatoid arthritis

Identification of rare disease genes as drivers of common diseases through tissue-specific gene regulatory networks

Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A

The RA-MAP Consortium: a working model for academia–industry collaboration

Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data

Oral Anti-Tumour Necrosis Factor Domain Antibody V565 Provides High Intestinal Concentrations, and Reduces Markers of Inflammation in Ulcerative Colitis Patients

RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients

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