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Showing 101–150 of 240 results

Advanced filters: Author: P. P. Orth Clear advanced filters

Pancreatic microexons regulate islet function and glucose homeostasis

In this study, Juan-Mateu et al. discover microexons that modulate insulin secretion in the pancreas in response to glucose levels in beta cell lines and mouse islets. Human genetic variants modulating these islet microexons are associated with type 2 diabetes risk.

Jonàs Juan-Mateu
Simon Bajew
Manuel Irimia
Research09 Feb 2023
Nature Metabolism

Volume: 5, P: 219-236
Cytotoxic therapy with etoposide and cisplatin in advanced adrenocortical carcinoma

R Bonacci
A Gigliotti
M Schlumberger
Research01 Aug 1998
British Journal of Cancer

Volume: 78, P: 546-549
Visualizing band selective enhancement of quasiparticle lifetime in a metallic ferromagnet

The onset of a ferromagnetic order in metals is often accompanied by a drop in resistivity; however, its effect on electronic quasiparticles is less understood. Here the authors present spectroscopic evidence of quasiparticle lifetime enhancement below the ferromagnetic transition temperature in EuCd₂As₂.

Na Hyun Jo
Yun Wu
Adam Kaminski
ResearchOpen Access09 Dec 2021
Nature Communications

Volume: 12, P: 1-7
Tectonic and magmatic transitions in the Western Great Basin, USA

David S. Ormerod
Christopher J. Hawkesworth
Martin A. Menzies
Research26 May 1988
Nature

Volume: 333, P: 349-353
Vestigial singlet pairing in a fluctuating magnetic triplet superconductor and its implications for graphene superlattices

P. Poduval et al. theoretically study the nonzero-temperature vestigial phases of a 2D model exhibiting both triplet superconductivity and magnetism. They show that this model allows for a unique superconducting state in which the condensate consists of entities with three electrons and one hole, with properties similar to those seen in experiments on moiré systems.

Prathyush P. Poduval
Mathias S. Scheurer
ResearchOpen Access24 Feb 2024
Nature Communications

Volume: 15, P: 1-9
On the Biologic Origin of C₆-C₁₀-Dicarboxylic and C₆-C₁₀-ω-1-Hydroxy Monocarboxylic Acids in Human and Rat with Acyl-CoA Dehydrogenation Deficiencies: in Vitro Studies on the ω- and ω-1-Oxidation of Medium-Chain (C₆-C₁₂) Fatty Acids in Human and Rat Liver

N Gregersen
P B Mortensen
S Kølvraa
Research01 Oct 1983
Pediatric Research

Volume: 17, P: 828-834
The molecular genetics of embryonic pattern formation in Drosophila

P. W. Ingham
Amendments and Corrections20 Oct 1988
Nature

Volume: 335, P: 744
A probability-based approach for the analysis of large-scale RNAi screens

Renate König
Chih-yuan Chiang
Sumit K Chanda
Research09 Sept 2007
Nature Methods

Volume: 4, P: 847-849
Beneficial Effects of Nalmefene Augmentation in Neuroleptic-Stabilized Schizophrenic Patients

Mark Hyman Rapaport
Owen Wolkowitz
David Pickar
Research01 Sept 1993
Neuropsychopharmacology

Volume: 9, P: 111-115
Bacterial virulence proteins as tools to rewire kinase pathways in yeast and immune cells

Virulence factors from two bacteria are used to reprogram intracellular signalling in yeast and immune T cells, illustrating how pathogens can provide a toolkit to engineer cells for biotechnological or therapeutic applications.

Ping Wei
Wilson W. Wong
Wendell A. Lim
Research22 Jul 2012
Nature

Volume: 488, P: 384-388
TDP-43 and RNA form amyloid-like myo-granules in regenerating muscle

Cytoplasmic, amyloid-like oligomeric assemblies that contain TDP-43 are increased in damaged tissues with elevated regeneration, thereby enhancing the possibility of amyloid fibre formation and/or aggregation of TDP-43 in disease.

Thomas O. Vogler
Joshua R. Wheeler
Roy Parker
Research31 Oct 2018
Nature

Volume: 563, P: 508-513
Further development of hybrid functional electrical stimulation orthoses

L Yang
M H Granat
D I Rowley
Research01 Oct 1996
Spinal Cord

Volume: 34, P: 611-614
A functional genomics approach to the mode of action of apratoxin A

Hendrik Luesch
Sumit K Chanda
Peter G Schultz
Research12 Feb 2006
Nature Chemical Biology

Volume: 2, P: 158-167
Peripapillary subretinal neovascular membranes: The natural history

G Silvestri
D B Archer
P B Johnston
Research01 May 1993
Eye

Volume: 7, P: 398-402
Sécheresse 1893, ses Causes

W. E. P.
Books & Arts19 Oct 1893
Nature

Volume: 48, P: 587-588
In situ hybridization of viral nucleic acids in tumour cells

J K McDougall
P H Gallimore
K W Jones
Research01 Jul 1973
British Journal of Cancer

Volume: 28, P: 87
State-of-the-art global models underestimate impacts from climate extremes

Impact models projections are used in integrated assessments of climate change. Here the authors test systematically across many important systems, how well such impact models capture the impacts of extreme climate conditions.

Jacob Schewe
Simon N. Gosling
Lila Warszawski
ResearchOpen Access01 Mar 2019
Nature Communications

Volume: 10, P: 1-14
Split superconducting and time-reversal symmetry-breaking transitions in Sr₂RuO₄ under stress

When strain is applied to strontium ruthenate, superconductivity emerges at a different temperature to the breaking of time-reversal symmetry. This indicates that the superconductivity could have a chiral d-wave order parameter.

Vadim Grinenko
Shreenanda Ghosh
Hans-Henning Klauss
Research04 Mar 2021
Nature Physics

Volume: 17, P: 748-754
Applications of the European Parkinson’s Disease Association sponsored Parkinson’s Disease Composite Scale (PDCS)

Roberta Balestrino
Carlos Alberto Hurtado-Gonzalez
Zoe Katsarou
ResearchOpen Access27 Nov 2019
npj Parkinson's Disease

Volume: 5, P: 1-7
Ecophysiology

P. D. Moore
Books & Arts05 May 1977
Nature

Volume: 267, P: 88
Feeding Fruit Crops

D. W. P. GREENHAM
Books & Arts01 Jul 1967
Nature

Volume: 215, P: 107
Five human tumour cell lines derived from a primary squamous carcinoma of the tongue, two subsequent local recurrences and two nodal metastases

D M Easty
G C Easty
T James
Research01 Sept 1981
British Journal of Cancer

Volume: 44, P: 363-370
The Premarket Review Process for Class III Devices

William H. E. von Oehsen
Research01 Sept 1989
Bio/Technology

Volume: 7, P: 897-902
Metal-Insulator Transition of strained SmNiO₃ Thin Films: Structural, Electrical and Optical Properties

B. Torriss
J. Margot
M. Chaker
ResearchOpen Access18 Jan 2017
Scientific Reports

Volume: 7, P: 1-9
The greenhouse gas offset potential from seagrass restoration

Matthew P. J. Oreska
Karen J. McGlathery
Lindsay Mullins
ResearchOpen Access30 Apr 2020
Scientific Reports

Volume: 10, P: 1-15
On the Mammals and Winter Birds of East Florida: with an Examination of Certain Assumed Specific Characters in Bird Faunæ of Eastern North America

P. L. S.
Books & Arts23 Nov 1871
Nature

Volume: 5, P: 58-59
Bacterial Diseases of Plants ¹

M. C. P.
News10 Dec 1914
Nature

Volume: 94, P: 404-405
Intertwined vestigial orders in stacked magnetic flatlands

Dimensionality tuning can control fluctuations and induce complex phase diagrams with multiple orders and transitions among them. Now, experiments demonstrate intertwined vestigial order in the two- to three-dimensional crossover region in a van der Waals magnet.

Ana-Marija Nedić
Peter P. Orth
News & Views18 Sept 2024
Nature Physics

Volume: 20, P: 1694-1695
The Yersinia Ysc–Yop 'Type III' weaponry

Guy R. Cornelis
Reviews01 Oct 2002
Nature Reviews Molecular Cell Biology

Volume: 3, P: 742-753
Urinary epidermal growth factor (hEGF) levels in patients with carcinomas of the breast, colon and rectum

JW Sweetenham
DE Davies
P Alexander
Research01 Sept 1990
British Journal of Cancer

Volume: 62, P: 459-461
Dr. H. O. Jones, F.R.S.

K. J. P. O.
News22 Aug 1912
Nature

Volume: 89, P: 638
Structure and expression of c-myc and c-fos proto-oncogenes in thyroid carcinomas

P Terrier
Z-M Sheng
G Riou
Research01 Jan 1988
British Journal of Cancer

Volume: 57, P: 43-47
Die Holarktis:

B. P. UVAROV
Books & Arts24 Jul 1937
Nature

Volume: 140, P: 129-130
Author Correction: Serum proteomics reveal APOE-ε4-dependent and APOE-ε4-independent protein signatures in Alzheimer’s disease

Elisabet A. Frick
Valur Emilsson
Vilmundur Gudnason
Amendments and CorrectionsOpen Access16 Sept 2024
Nature Aging

Volume: 4, P: 1509
Apoptosis, in human monocytic THP.1 cells, results in the release of cytochrome c from mitochondria prior to their ultracondensation, formation of outer membrane discontinuities and reduction in inner membrane potential

Jianguo Zhuang
David Dinsdale
Gerald M Cohen
Research03 Nov 1998
Cell Death & Differentiation

Volume: 5, P: 953-962
72 VALUE OF PLASMA THYROGLOBULIN (Tg) MEASUREMENT IN THE DIAGNOSIS AND TREATMENT OF CONGENITAL HYPOTHYROIDISM

A Tar
J Léger
P Czernichow
Research01 Jun 1985
Pediatric Research

Volume: 19, P: 615
Motor cortex plasticity response to acute cardiorespiratory exercise and intermittent theta-burst stimulation is attenuated in premanifest and early Huntington’s disease

Sophie C. Andrews
Dylan Curtin
Julie C. Stout
ResearchOpen Access20 Jan 2022
Scientific Reports

Volume: 12, P: 1-11
O-GlcNAcylation controls pro-fibrotic transcriptional regulatory signaling in myofibroblasts

Ninon Very
Clémence Boulet
Jérôme Eeckhoute
ResearchOpen Access03 Jun 2024
Cell Death & Disease

Volume: 15, P: 1-22
Comparison of 432 Pseudomonas strains through integration of genomic, functional, metabolic and expression data

Jasper J. Koehorst
Jesse C. J. van Dam
Peter J. Schaap
ResearchOpen Access06 Dec 2016
Scientific Reports

Volume: 6, P: 1-13
Comparison of Adrenocorticotropin and Adrenal Steroid Responses to Corticotropin-Releasing Hormone Versus Metyrapone Testing in Patients with Hypopituitarism

Linda Riddick
George P Chrousos
Songya Pang
Research01 Aug 1994
Pediatric Research

Volume: 36, P: 215-220
The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERα

Ablation of the large tumour suppressor kinases 1 and 2 promotes a luminal breast cell phenotype through stabilization of oestrogen receptor-α, thereby changing human breast cell fate.

Adrian Britschgi
Stephan Duss
Mohamed Bentires-Alj
Research09 Jan 2017
Nature

Volume: 541, P: 541-545
Terahertz-light quantum tuning of a metastable emergent phase hidden by superconductivity

THz pump–probe experiments of superconducting Nb₃Sn reveal that a metastable phase is induced for excitation fields around 250 kV cm⁻¹.

X. Yang
C. Vaswani
J. Wang
Research04 Jun 2018
Nature Materials

Volume: 17, P: 586-591
Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity

In several human and mouse cancer cell lines and carcinomas, a sapienate biosynthesis pathway underpins metabolic plasticity by allowing these cells to bypass stearoyl-CoA desaturase-dependent fatty acid desaturation.

Kim Vriens
Stefan Christen
Sarah-Maria Fendt
Research06 Feb 2019
Nature

Volume: 566, P: 403-406
EndoBind detects endogenous protein-protein interactions in real time

Bill et al describe two high-throughput methods to detect protein-protein interactions in cells in real-time using the split-NanoLuciferase-complementation system. They demonstrate the methods can detect exogenously (RT-bind) or endogenously (EndoBind) expressed proteins, respectively.

Anke Bill
Sheryll Espinola
Frederick J. King
ResearchOpen Access15 Sept 2021
Communications Biology

Volume: 4, P: 1-6
Kant's Cosmogony as in his Essay on the Retardation of the Rotation of the Earth, and his Natural History and Theory of the Heavens

W. E. P.
Books & Arts28 Feb 1901
Nature

Volume: 63, P: 413-415
The Atomic Theory

M. M. P. M.
Books & Arts04 Nov 1880
Nature

Volume: 23, P: 5-7
Transcriptomic plasticity of the hypothalamic osmoregulatory control centre of the Arabian dromedary camel

Comparative transcriptomic analyses between dromedary camels and rats provide insight into water homeostasis gene responses in animals under water stress conditions.

Panjiao Lin
Benjamin T. Gillard
David Murphy
ResearchOpen Access23 Sept 2022
Communications Biology

Volume: 5, P: 1-15
STEC-HUS, atypical HUS and TTP are all diseases of complement activation

Atypical haemolytic uraemic syndrome (HUS), Shiga toxin-producingEscherichia coli-associated HUS and thrombotic thrombocytopaenic purpura are diseases characterized by microvascular thrombosis, with subsequent dysfunction of affected organs. In this Review, the authors discuss data indicating that complement dysregulation is a common pathogenetic effector of all three diseases, and describe the emerging evidence indicating that targeting complement may effectively treat these disease entities.

Marina Noris
Federica Mescia
Giuseppe Remuzzi
Reviews18 Sept 2012
Nature Reviews Nephrology

Volume: 8, P: 622-633
COMBINED MINERALCORTICOID - CORTISONE VERSUS CORTISONE TREATMENT IN CONGENITAL ADRENAL HYTERPLASIA

K Snellman
P Olin
Research01 Aug 1975
Pediatric Research

Volume: 9, P: 690
Human host factors required for influenza virus replication

The small coding capacity of the influenza A virus demands that the virus use the host cellular machinery for many aspects of its life cycle. An integrated systems approach, based on genome-wide RNA interference screening, is now used to identify 295 cellular cofactors required for early-stage influenza virus replication. Knowledge of these host cell requirements provides further targets that could be pursued for antiviral drug development.

Renate König
Silke Stertz
Sumit K. Chanda
Research21 Dec 2009
Nature

Volume: 463, P: 813-817

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