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Showing 1–3 of 3 results
Advanced filters: Author: PHILIP E. AURON Clear advanced filters

  • Alterations in the tumour suppressor genes STK11 and/or KEAP1 can identify patients with advanced non-small-cell lung cancer who are likely to benefit from combinations of PD-(L)1 and CTLA4 immune checkpoint inhibitors added to chemotherapy.

    • Ferdinandos Skoulidis
    • Haniel A. Araujo
    • John V. Heymach
    ResearchOpen Access
    Nature
    Volume: 635, P: 462-471

  • A pediatric cancer dependency map generated with genome-scale CRISPR–Cas9 loss-of-function screens in 82 pediatric cancer cell lines highlights genetic dependencies across a range of tumor types.

    • Neekesh V. Dharia
    • Guillaume Kugener
    • Kimberly Stegmaier
    Research
    Nature Genetics
    Volume: 53, P: 529-538