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Showing 1–3 of 3 results
Advanced filters: Author: Pankaj K. Agarwalla Clear advanced filters

  • Gelareh Zadeh, Kenneth Aldape and colleagues present an integrative genomic analysis of schwannomas. In addition to finding recurrent mutations in ARID1A, ARID1B and DDR1, they identify a recurrent SH3PXD2A-HTRA1 fusion that confers increased proliferation, invasion and in vivo transformation, and is associated with sensitivity to MEK inhibition.

    • Sameer Agnihotri
    • Shahrzad Jalali
    • Gelareh Zadeh
    Research
    Nature Genetics
    Volume: 48, P: 1339-1348