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Advanced filters: Author: Papiya Sinha Clear advanced filters

  • Boztug and colleagues identify an immunodeficient patient with a deficiency in the guanine-nucleotide-exchange factor RASGRP1. They find that human RASGRP1 is important for the function of T cells, B cells and NK cells and that it has a role in the regulation of the cytoskeleton.

    • Elisabeth Salzer
    • Deniz Cagdas
    • Kaan Boztug
    Research
    Nature Immunology
    Volume: 17, P: 1352-1360