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Showing 1–2 of 2 results
Advanced filters: Author: Parthive H. Patel Clear advanced filters

  • Epithelia are exposed to diverse types of environmental stress, but the mechanisms by which epithelial cells sense stress are not well understood. Here, the authors show that a Nox-ROS-Ask1-MKK3-p38 signaling axis integrates various types of stress to promote intestinal regeneration.

    • Parthive H. Patel
    • Clothilde Pénalva
    • Bruce A. Edgar
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-14

  • Patel et al. report that Drosophila intestinal stem cell tumours are generated by stress- and EGFR-signalling, followed by extrusion of neighbouring enterocytes, enterocytic cytokine expression and paracrine signalling for tumour growth.

    • Parthive H. Patel
    • Devanjali Dutta
    • Bruce A. Edgar
    Research
    Nature Cell Biology
    Volume: 17, P: 1182-1192