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Showing 1–7 of 7 results
Advanced filters: Author: Pat O’Brien Clear advanced filters

  • The impacts of maternal SARS-CoV-2 infection on newborns are not well understood. Here, the authors perform a national cohort study using data on births in the UK from March 2020—March 2022 and find that moderate to severe maternal COVID-19 was associated with adverse perinatal outcomes.

    • Hilde Marie Engjom
    • Rema Ramakrishnan
    • Marian Knight
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-9

  • Pregnant women have been disproportionately under-vaccinated against COVID-19, partly because they were excluded from initial trials. This systematic review and meta-analysis supports efficacy of vaccination in pregnancy, and finds no evidence of adverse maternal or perinatal outcomes.

    • Smriti Prasad
    • Erkan Kalafat
    • Asma Khalil
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-8

  • Combination of epidemiology, preclinical models and ultradeep DNA profiling of clinical cohorts unpicks the inflammatory mechanism by which air pollution promotes lung cancer

    • William Hill
    • Emilia L. Lim
    • Charles Swanton
    Research
    Nature
    Volume: 616, P: 159-167

  • In the current monkeypox outbreak, vaccination and treatment of pregnant women are recommended only if the benefits outweigh risks, but the extremely sparse data available limit evidence-based recommendations. We must facilitate a unified consensus approach to rapidly collect robust data. Two years into the COVID-19 pandemic, monkeypox has emerged as yet another challenge to the mother-fetus dyad, potentially placing both at risk, if exposed.

    • Asma Khalil
    • Athina Samara
    • Shamez Ladhani
    Comments & OpinionOpen Access
    Nature Communications
    Volume: 13, P: 1-4

  • The genome of the southeast Asian orang-utan has been sequenced. The draft assembly of a Sumatran individual alongside sequence data from five Sumatran and five Bornean orang-utan genomes is presented. The resources and analyses described offer new opportunities in evolutionary genomics, insights into hominid biology, and an extensive database of variation for conservation efforts.

    • Devin P. Locke
    • LaDeana W. Hillier
    • Richard K. Wilson
    ResearchOpen Access
    Nature
    Volume: 469, P: 529-533

  • Drug repositioning and repurposing can enhance traditional drug development efforts and could accelerate the identification of new treatments. In this Review, Ballard and colleagues highlight priority compounds for repurposing for the treatment of Alzheimer disease.

    • Clive Ballard
    • Dag Aarsland
    • Janet Sultana
    Reviews
    Nature Reviews Neurology
    Volume: 16, P: 661-673