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Showing 1–3 of 3 results
Advanced filters: Author: Patrick Blader Clear advanced filters
  • The evolutionary origin of habenular asymmetries is elusive. Here they show morphological and molecular conservations indicative of an ancient origin in vertebrates and identify Wnt signaling as a core mechanism underlying their formation and diversification.

    • Maxence Lanoizelet
    • Léo Michel
    • Sylvie Mazan
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-16
  • Cyclopia — the development of a single, central eye — occurs because of a lack of, or defect in, development of the ventral (fore) brain. Three groups have studied this developmental pathway in the zebrafish, and have identified two of the genes involved. Fish that lack the cyclops (cyc) and squint (sqt) genes are cyclopic. Moreover, the authors have found that Cyclops belongs to the transforming growth factor-β family of proteins.

    • Patrick Blader
    • Uwe Strähle
    News & Views
    Nature
    Volume: 395, P: 112-113
  • The authors identify a hemispheric asymmetry in neurogenesis in adult zebrafish. This asymmetry could be reversed by olfactory sensory deprivation or decreasing Notch signaling on the left side. Behavioral responses of fish to olfactory cues depended on the left olfactory epithelium, which may be a result of this asymmetry in neurogenesis.

    • Norihito Kishimoto
    • Kazuhide Asakawa
    • Kazunobu Sawamoto
    Research
    Nature Neuroscience
    Volume: 16, P: 884-888