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Showing 151–200 of 212 results

Advanced filters: Author: Patrick D Robertson Clear advanced filters

Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution

LaDeana W. Hillier
Webb Miller
Richard K. Wilson
Research09 Dec 2004
Nature

Volume: 432, P: 695-716
FLAG-idarubicin and allogeneic stem cell transplantation for Ph-positive ALL beyond first remission

M Deane
M Koh
HG Prentice
Research17 Dec 1998
Bone Marrow Transplantation

Volume: 22, P: 1137-1143
Ovarian carcinoma cells are effectively transfected by polyethylenimine (PEI) derivatives

Laurent Poulain
Christelle Ziller
Jean-Paul Behr
Research15 Jun 2000
Cancer Gene Therapy

Volume: 7, P: 644-652
The zebrafish reference genome sequence and its relationship to the human genome

A high-quality sequence assembly of the zebrafish genome reveals the largest gene set of any vertebrate and provides information on key genomic features, and comparison to the human reference genome shows that approximately 70% of human protein-coding genes have at least one clear zebrafish orthologue.

Kerstin Howe
Matthew D. Clark
Derek L. Stemple
ResearchOpen Access17 Apr 2013
Nature

Volume: 496, P: 498-503
Author Correction: Delayed production of neutralizing antibodies correlates with fatal COVID-19

Carolina Lucas
Jon Klein
Akiko Iwasaki
Amendments and Corrections18 Jun 2021
Nature Medicine

Volume: 27, P: 1309
Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient

Patterning of the human neural tube is modeled in a microfluidic device.

Pedro Rifes
Marc Isaksson
Agnete Kirkeby
Research25 May 2020
Nature Biotechnology

Volume: 38, P: 1265-1273
Establishment of mouse expanded potential stem cells

Cultures of expanded potential stem cells can be established from individual eight-cell blastomeres, and by direct conversion of mouse embryonic stem cells and induced pluripotent stem cells, highlighting the feasibility of establishing expanded potential stem cells for other mammalian species.

Jian Yang
David J. Ryan
Pentao Liu
Research11 Oct 2017
Nature

Volume: 550, P: 393-397
Effects of spironolactone on exercise blood pressure in patients at increased risk of developing heart failure: report from the HOMAGE trial

Fang-Fei Wei
Pierpaolo Pellicori
Faiez Zannad
ResearchOpen Access06 Sept 2024
Hypertension Research

Volume: 47, P: 3225-3236
Socioeconomic deprivation and illness trajectory in the Scottish population after COVID-19 hospitalization

Morrow et al. evaluate the clinical and social parameters of Scottish patients who were previously admitted to hospital with SARS-CoV-2 infection. They report that socioeconomic deprivation influences illness trajectory after COVID-19.

Andrew J. Morrow
Robert Sykes
Colin Berry
ResearchOpen Access28 Feb 2024
Communications Medicine

Volume: 4, P: 1-7
Identification of rare-disease genes using blood transcriptome sequencing and large control cohorts

A diagnostic tool based on blood RNA-seq is shown to identify causal genes and variants linked to clinical phenotypes in individuals with rare diseases for which whole-exome genetic sequencing was uninformative.

Laure Frésard
Craig Smail
Stephen B. Montgomery
Research03 Jun 2019
Nature Medicine

Volume: 25, P: 911-919
Author Correction: Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial

Philippe Bégin
Jeannie Callum
Donald M. Arnold
Amendments and CorrectionsOpen Access12 Jan 2022
Nature Medicine

Volume: 28, P: 212
Transcription elongation factors represent in vivo cancer dependencies in glioblastoma

An in vivo RNA interference screening strategy in glioblastoma enabled the identification of a host of epigenetic targets required for glioblastoma cell survival that were not identified by parallel standard screening in cell culture, including the transcription pause–release factor JMJD6, and could be a powerful tool to uncover new therapeutic targets in cancer.

Tyler E. Miller
Brian B. Liau
Jeremy N. Rich
Research05 Jul 2017
Nature

Volume: 547, P: 355-359
RNA targeting with CRISPR–Cas13

The class 2 type VI RNA-guided RNA-targeting CRISPR–Cas effector Cas13 can be engineered for RNA knockdown and binding, expanding the CRISPR toolset with a flexible platform for studying RNA in mammalian cells and therapeutic development.

Omar O. Abudayyeh
Jonathan S. Gootenberg
Feng Zhang
Research04 Oct 2017
Nature

Volume: 550, P: 280-284
Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis

Joana Carlevaro-Fita, Andrés Lanzós et al. present the Cancer LncRNA Census (CLC), a manually curated dataset of 122 long noncoding RNAs (lncRNAs) with experimentally-validated functions in cancer based on data from the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium. CLC lncRNAs have unique gene features, and a number display evidence for cancer-driving functions that are conserved from humans to mice.

Joana Carlevaro-Fita
Andrés Lanzós
Christian von Mering
ResearchOpen Access05 Feb 2020
Communications Biology

Volume: 3, P: 1-16
Publisher Correction: Genomic reconstruction of the SARS CoV-2 epidemic in England

Harald S. Vöhringer
Theo Sanderson
Moritz Gerstung
Amendments and CorrectionsOpen Access07 Jun 2022
Nature

Volume: 606, P: E18
Do Age of Onset and Course of Illness Predict Different Treatment Outcome among DSM IV Depressive Disorders with Atypical Features?

Jonathan W Stewart
Patrick J McGrath
Frederic M Quitkin
Research12 Jul 2001
Neuropsychopharmacology

Volume: 26, P: 237-245
Genomic epidemiology of SARS-CoV-2 in a university outbreak setting and implications for public health planning

Sema Nickbakhsh
Joseph Hughes
Alison Smith-Palmer
ResearchOpen Access19 Jul 2022
Scientific Reports

Volume: 12, P: 1-17
Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

Praveen Surendran
Elena V. Feofanova
Joanna M. M. Howson
Amendments and Corrections16 Mar 2021
Nature Genetics

Volume: 53, P: 762
A comprehensive iterative approach is highly effective in diagnosing individuals who are exome negative

Vandana Shashi
Kelly Schoch
Allison Zheng
Research15 Jun 2018
Genetics in Medicine

Volume: 21, P: 161-172
Targeting the PML/RARα translocation product triggers apoptosis in promyelocytic leukemia cells

Kathryn Nason-Burchenal
Garry Takle
Ethan Dmitrovsky
Research09 Oct 1998
Oncogene

Volume: 17, P: 1759-1768
Publisher Correction: Stroke genetics informs drug discovery and risk prediction across ancestries

Aniket Mishra
Rainer Malik
Stephanie Debette
Amendments and CorrectionsOpen Access14 Nov 2022
Nature

Volume: 612, P: E7
Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

Lavinia Paternoster and colleagues report the results of a large, multi-ancestry genome-wide association study of atopic dermatitis. They identify ten new susceptibility loci harboring candidate genes involved in innate host defense and T cell function.

Lavinia Paternoster
Marie Standl
Stephan Weidinger
Research19 Oct 2015
Nature Genetics

Volume: 47, P: 1449-1456
PPD ACT: an app-based genetic study of postpartum depression

Jerry Guintivano
Holly Krohn
Samantha Meltzer-Brody
ResearchOpen Access29 Nov 2018
Translational Psychiatry

Volume: 8, P: 1-14
Looking beyond the exome: a phenotype-first approach to molecular diagnostic resolution in rare and undiagnosed diseases

Loren D M Pena
Yong-Hui Jiang
Vandana Shashi
Research14 Sept 2017
Genetics in Medicine

Volume: 20, P: 464-469
Immortalized N/TERT keratinocytes as an alternative cell source in 3D human epidermal models

Jos P. H. Smits
Hanna Niehues
Ellen H. van den Bogaard
ResearchOpen Access19 Sept 2017
Scientific Reports

Volume: 7, P: 1-14
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Valérie Turcot
Yingchang Lu
Ruth J. F. Loos
Amendments and Corrections16 Mar 2018
Nature Genetics

Volume: 50, P: 766-767
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Valérie Turcot
Yingchang Lu
Ruth J. F. Loos
Amendments and Corrections16 Mar 2018
Nature Genetics

Volume: 50, P: 765-766
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Valérie Turcot
Yingchang Lu
Ruth J. F. Loos
Amendments and Corrections03 Jun 2019
Nature Genetics

Volume: 51, P: 1191-1192
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

Stephen Sawcer
Garrett Hellenthal
Alastair Compston
Research10 Aug 2011
Nature

Volume: 476, P: 214-219
A resource of lipidomics and metabolomics data from individuals with undiagnosed diseases

Jennifer E. Kyle
Kelly G. Stratton
Thomas O. Metz
ResearchOpen Access21 Apr 2021
Scientific Data

Volume: 8, P: 1-12
Common loss of far-red light photoacclimation in cyanobacteria from hot and cold deserts: a case study in the Chroococcidiopsidales

Laura A. Antonaru
Vera M. Selinger
Dennis J. Nürnberg
ResearchOpen Access19 Oct 2023
ISME Communications

Volume: 3, P: 1-9
Author Correction: Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Dami A. Collier
Anna De Marco
Ravindra K. Gupta
Amendments and Corrections21 Jul 2022
Nature

Volume: 608, P: E24
Author Correction: SARS-CoV-2 evolution during treatment of chronic infection

Steven A. Kemp
Dami A. Collier
Ravindra K. Gupta
Amendments and Corrections21 Jul 2022
Nature

Volume: 608, P: E23
Gut microbiome composition and function in experimental colitis during active disease and treatment-induced remission

Michelle G Rooks
Patrick Veiga
Wendy S Garrett
ResearchOpen Access06 Feb 2014
The ISME Journal

Volume: 8, P: 1403-1417
COVID-19 due to the B.1.617.2 (Delta) variant compared to B.1.1.7 (Alpha) variant of SARS-CoV-2: a prospective observational cohort study

Kerstin Kläser
Erika Molteni
Emma L. Duncan
ResearchOpen Access28 Jun 2022
Scientific Reports

Volume: 12, P: 1-17
Distinct clinical symptom patterns in patients hospitalised with COVID-19 in an analysis of 59,011 patients in the ISARIC-4C study

Jonathan E. Millar
Lucile Neyton
Peter Young
ResearchOpen Access27 Apr 2022
Scientific Reports

Volume: 12, P: 1-13
Author Correction: Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models

Rosa Lundbye Allesøe
Agnete Troen Lundgaard
Moustafa Abdalla
Amendments and CorrectionsOpen Access02 May 2023
Nature Biotechnology

Volume: 41, P: 1026
Automated syndrome diagnosis by three-dimensional facial imaging

Benedikt Hallgrímsson
J. David Aponte
Ophir D. Klein
ResearchOpen Access01 Jun 2020
Genetics in Medicine

Volume: 22, P: 1682-1693
Clinical findings and a DNA methylation signature in kindreds with alterations in ZNF711

Jiyong Wang
Aidin Foroutan
Roger E. Stevenson
Research07 Jan 2022
European Journal of Human Genetics

Volume: 30, P: 420-427
Elevated Dopamine D_2/3 Receptor Availability in Obese Individuals: A PET Imaging Study with [¹¹C](+)PHNO

Edward C Gaiser
Jean-Dominique Gallezot
David Matuskey
Research04 Jul 2016
Neuropsychopharmacology

Volume: 41, P: 3042-3050
A genomic data archive from the Network for Pancreatic Organ donors with Diabetes

Daniel J. Perry
Melanie R. Shapiro
Todd M. Brusko
ResearchOpen Access26 May 2023
Scientific Data

Volume: 10, P: 1-16
Rapid optimisation of fragments and hits to lead compounds from screening of crude reaction mixtures

Fragment-based screening offers a valuable method for identifying ligands and can be expanded to crude reaction mixtures. Here, high-throughput crystallographic screening of crystals soaked with crude reaction mixtures is assessed as a method to rapidly obtain ligands with improved affinity.

Lisa M. Baker
Anthony Aimon
Roderick E. Hubbard
ResearchOpen Access02 Sept 2020
Communications Chemistry

Volume: 3, P: 1-11
Contrasting genetic trajectories of endangered and expanding red fox populations in the western U.S

Cate B. Quinn
Sophie Preckler-Quisquater
Benjamin N. Sacks
ResearchOpen Access21 Mar 2022
Heredity

Volume: 129, P: 123-136
High-resolution epitope mapping and characterization of SARS-CoV-2 antibodies in large cohorts of subjects with COVID-19

Using a high throughput, random bacterial peptide display approach applied to patient serum samples, Haynes, Kamath, Bozekowski et al identify the antigens and epitopes that elicit a SARS-CoV-2 humoral response. They identify differences depending on disease severity and further in silico analysis suggests decreased epitope signal for Q677P but not for D614G mutant SARSCoV-2 strains.

Winston A. Haynes
Kathy Kamath
John C. Shon
ResearchOpen Access22 Nov 2021
Communications Biology

Volume: 4, P: 1-14
ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19

Ali Abbas
Sheryl Ann Abdukahil
Luis Felipe Reyes
ResearchOpen Access30 Jul 2022
Scientific Data

Volume: 9, P: 1-22
Phenotypic expansion of CACNA1C-associated disorders to include isolated neurological manifestations

Lance H. Rodan
Rebecca C. Spillmann
Vandana Shashi
Research23 Jun 2021
Genetics in Medicine

Volume: 23, P: 1922-1932
Breast cancer management pathways during the COVID-19 pandemic: outcomes from the UK ‘Alert Level 4’ phase of the B-MaP-C study

Rajiv V. Dave
Baek Kim
Zaid Al-Ishaq
ResearchOpen Access25 Mar 2021
British Journal of Cancer

Volume: 124, P: 1785-1794
Genetic Interactions with Age, Sex, Body Mass Index, and Hypertension in Relation to Atrial Fibrillation: The AFGen Consortium

Lu-Chen Weng
Kathryn L. Lunetta
Steven A. Lubitz
ResearchOpen Access12 Sept 2017
Scientific Reports

Volume: 7, P: 1-11
The p107 tumor suppressor induces stable E2F DNA binding to repress target promoters

Robert J O'Connor
Joel E Schaley
Patrick Hearing
Research05 Apr 2001
Oncogene

Volume: 20, P: 1882-1891
Four consecutive yearly point-prevalence studies in Wales indicate lack of improvement in sepsis care on the wards

Maja Kopczynska
Harry Unwin
Judith E. Hall
ResearchOpen Access10 Aug 2021
Scientific Reports

Volume: 11, P: 1-12

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