Nature Search

The vaginal microbiome of pregnant women is less rich and diverse, with lower prevalence of Mollicutes, compared to non-pregnant women

Aline C. Freitas
Bonnie Chaban
Mark Yudin
ResearchOpen Access23 Aug 2017
Scientific Reports

Volume: 7, P: 1-16
Decoding post-transcriptional regulatory networks by RNA-linked CRISPR screening in human cells

This work presents ReLiC, an RNA-linked CRISPR platform that enables dissection of RNA metabolic processes by targeting over 2,000 RNA-associated genes, revealing key regulators on RNA splicing, translation and decay.

Patrick J. Nugent
Heungwon Park
Arvind Rasi Subramaniam
Research29 May 2025
Nature Methods

Volume: 22, P: 1237-1246
HPV infection alters vaginal microbiome through down-regulating host mucosal innate peptides used by Lactobacilli as amino acid sources

Here, the authors show that HPV infection leads to downregulation of host mucosal innate peptides, which are in turn used by predominant Lactobacillus species as amino acid source, promoting ultimately an imbalance in the vaginal flora.

Alizee Lebeau
Diane Bruyere
Michael Herfs
ResearchOpen Access28 Feb 2022
Nature Communications

Volume: 13, P: 1-20
The composition of human vaginal microbiota transferred at birth affects offspring health in a mouse model

Exposure at birth to maternal microbiota has significant effects on offspring health and development. Here, the authors validate a model where inoculation of mice at birth with human vaginal microbiota produces significant effects on offspring health that are further amplified by an unhealthy prenatal environment.

Eldin Jašarević
Elizabeth M. Hill
Tracy L. Bale
ResearchOpen Access01 Nov 2021
Nature Communications

Volume: 12, P: 1-16
Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept

The authors defined a roadmap for investigating the genetic covariance between structural or functional brain phenotypes and risk for psychiatric disorders. Their proof-of-concept study using the largest available common variant data sets for schizophrenia and volumes of several (mainly subcortical) brain structures did not find evidence of genetic overlap.

Barbara Franke
Jason L Stein
Patrick F Sullivan
Research01 Feb 2016
Nature Neuroscience

Volume: 19, P: 420-431
Synthesis of meta-substituted arene bioisosteres from [3.1.1]propellane

The potential power of the saturated carbocycle bicyclo[3.1.1]heptane as a beneficial motif for improving the pharmacokinetic and physicochemical properties of drug candidates is demonstrated.

Nils Frank
Jeremy Nugent
Edward A. Anderson
Research15 Sept 2022
Nature

Volume: 611, P: 721-726
Epigenome-wide meta-analysis of PTSD across 10 military and civilian cohorts identifies methylation changes in AHRR

PTSD has been associated with DNA methylation of specific loci in the genome, but studies have been limited by small sample sizes. Here, the authors perform a meta-analysis of DNA methylation data from 10 different cohorts and identify CpGs in AHRR that are associated with PTSD.

Alicia K. Smith
Andrew Ratanatharathorn
Caroline M. Nievergelt
ResearchOpen Access24 Nov 2020
Nature Communications

Volume: 11, P: 1-9
Author Correction: T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial

Katie J. Ewer
Jordan R. Barrett
Elizabeth Stafford
Amendments and Corrections21 May 2021
Nature Medicine

Volume: 27, P: 1116
Porous materials with optimal adsorption thermodynamics and kinetics for CO₂ separation

A series of porous crystalline materials known as metal–organic materials are prepared, and a full sorption study shows that controlled pore size (rather than large surface area) coupled with appropriate chemistry lead to materials exhibiting fast and highly selective CO₂ sorption.

Patrick Nugent
Youssef Belmabkhout
Michael J. Zaworotko
Research27 Feb 2013
Nature

Volume: 495, P: 80-84
Megahertz pulse trains enable multi-hit serial femtosecond crystallography experiments at X-ray free electron lasers

Free-electron lasers are capable of high repetition rates and it is assumed that protein crystals often do not survive the first X-ray pulse. Here the authors address these issues with a demonstration of multi-hit serial crystallography in which multiple FEL pulses interact with the sample without destroying it.

Susannah Holmes
Henry J. Kirkwood
Connie Darmanin
ResearchOpen Access11 Aug 2022
Nature Communications

Volume: 13, P: 1-13
Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses

Two doses of the coronavirus disease 2019 vaccine ChAdOx1 nCoV-19 boost antibody responses and functions in phase 1/2 trial participants.

Jordan R. Barrett
Sandra Belij-Rammerstorfer
Dalila Zizi
Research17 Dec 2020
Nature Medicine

Volume: 27, P: 279-288
DNA damage-induced cell cycle checkpoints and DNA strand break repair in development and tumorigenesis

Gopal K Dasika
Suh-Chin J Lin
Eva Y-H P Lee
Research04 Jan 2000
Oncogene

Volume: 18, P: 7883-7899
A novel in vitro metric predicts in vivo efficacy of inhaled silver-based antimicrobials in a murine Pseudomonas aeruginosa pneumonia model

Parth N. Shah
Kush N. Shah
Carolyn L. Cannon
ResearchOpen Access23 Apr 2018
Scientific Reports

Volume: 8, P: 1-14
Author Correction: Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses

Jordan R. Barrett
Sandra Belij-Rammerstorfer
Dalila Zizi
Amendments and Corrections06 May 2021
Nature Medicine

Volume: 27, P: 1113
Intracellular calcium regulates nonsense-mediated mRNA decay

Bioluminescence-based reporter system for monitoring nonsense-mediated mRNA decay (NMD) in live cells, which identifies a group of cardiac glycosides as potent inhibitors of NMD and intracellular calcium as a key regulator of NMD.

Andrew Nickless
Erin Jackson
Zhongsheng You
Research27 Jul 2014
Nature Medicine

Volume: 20, P: 961-966
T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial

A single dose of the ChAdOx1 nCoV-19 vaccine elicits antibodies and cytokine-producing T cells that might help control or prevent SARS-CoV-2 infection.

Katie J. Ewer
Jordan R. Barrett
Elizabeth Stafford
Research17 Dec 2020
Nature Medicine

Volume: 27, P: 270-278
Combining immune check-point blockade and cryoablation in an immunocompetent hormone sensitive murine model of prostate cancer

Benjamin Benzon
Stephanie A. Glavaris
Ashley E. Ross
Research20 Mar 2018
Prostate Cancer and Prostatic Diseases

Volume: 21, P: 126-136
Pubertal adversity alters chromatin dynamics and stress circuitry in the pregnant brain

Kathleen E. Morrison
Anthony B. Cole
Tracy L. Bale
Research11 Feb 2020
Neuropsychopharmacology

Volume: 45, P: 1263-1271
AusTraits, a curated plant trait database for the Australian flora

Daniel Falster
Rachael Gallagher
Kasia Ziemińska
ResearchOpen Access30 Sept 2021
Scientific Data

Volume: 8, P: 1-20
Differential predictors for alcohol use in adolescents as a function of familial risk

Mira Tschorn
Robert C. Lorenz
Amir Tahmasebi
ResearchOpen Access04 Mar 2021
Translational Psychiatry

Volume: 11, P: 1-11
Common and distinct patterns of grey-matter volume alteration in major depression and bipolar disorder: evidence from voxel-based meta-analysis

T Wise
J Radua
D Arnone
ResearchOpen Access24 May 2016
Molecular Psychiatry

Volume: 22, P: 1455-1463

Search

The vaginal microbiome of pregnant women is less rich and diverse, with lower prevalence of Mollicutes, compared to non-pregnant women

Decoding post-transcriptional regulatory networks by RNA-linked CRISPR screening in human cells

HPV infection alters vaginal microbiome through down-regulating host mucosal innate peptides used by Lactobacilli as amino acid sources

The composition of human vaginal microbiota transferred at birth affects offspring health in a mouse model

Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept

Synthesis of meta-substituted arene bioisosteres from [3.1.1]propellane

Epigenome-wide meta-analysis of PTSD across 10 military and civilian cohorts identifies methylation changes in AHRR

Author Correction: T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial

Porous materials with optimal adsorption thermodynamics and kinetics for CO₂ separation

Megahertz pulse trains enable multi-hit serial femtosecond crystallography experiments at X-ray free electron lasers

Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses

DNA damage-induced cell cycle checkpoints and DNA strand break repair in development and tumorigenesis

A novel in vitro metric predicts in vivo efficacy of inhaled silver-based antimicrobials in a murine Pseudomonas aeruginosa pneumonia model

Author Correction: Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses

Intracellular calcium regulates nonsense-mediated mRNA decay

T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial

Combining immune check-point blockade and cryoablation in an immunocompetent hormone sensitive murine model of prostate cancer

Pubertal adversity alters chromatin dynamics and stress circuitry in the pregnant brain

AusTraits, a curated plant trait database for the Australian flora

Differential predictors for alcohol use in adolescents as a function of familial risk

Common and distinct patterns of grey-matter volume alteration in major depression and bipolar disorder: evidence from voxel-based meta-analysis

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