In this study, the authors show that, in newborn cortical neurons, the TrkB and TrkC receptors are transactivated by the EGF receptor, rather than by their traditional ligands, BDNF and NT-3. This transactivation appears to be involved in the migration of these neurons from the ventricular zone to the cortical plate.
- Dirk Puehringer
- Nadiya Orel
- Michael Sendtner