Nature Search

Prognostic Value of Serum Hyaluronic Acid and Type I and III Procollagen Propeptides in Extrahepatic Biliary Atresia

Premila Trivedi
Anil Dhawan
Alex P Mowat
Research01 Oct 1995
Pediatric Research

Volume: 38, P: 568-573
EB1 regulates attachment of Ska1 with microtubules by forming extended structures on the microtubule lattice

Ska1 is a kinetochore-localised protein that couples kinetochore movement to microtubule (MT) depolymerisation. Here Thomas et al. show that the MT +TIP binding protein EB1 recruits Ska1 to the MT-kinetochore interface and stabilises the interaction between Ska1 and MTs.

Geethu E. Thomas
K. Bandopadhyay
Tapas K. Manna
ResearchOpen Access26 May 2016
Nature Communications

Volume: 7, P: 1-13
A genome-wide atlas of human cell morphology

An optical pooled cell profiling platform (PERISCOPE) based on Cell Painting and optical sequencing of molecular barcodes was used to develop the first unbiased genome-wide morphology-based perturbation atlas in human cells.

Meraj Ramezani
Erin Weisbart
James T. Neal
ResearchOpen Access27 Jan 2025
Nature Methods

Volume: 22, P: 621-633
Adaptive changes in the kinetochore architecture facilitate proper spindle assembly

Using light- and electron microscopy, Khodjakov, Mogilner and colleagues find that the shape of the kinetochore undergoes dramatic changes during mitosis. Computational analysis suggests that this facilitates correct chromosome attachment.

Valentin Magidson
Raja Paul
Alexey Khodjakov
Research10 Aug 2015
Nature Cell Biology

Volume: 17, P: 1134-1144
Context-specific regulation of surface and soluble IL7R expression by an autoimmune risk allele

Interleukin-7 (IL-7) is a central cytokine in T cell homeostasis. Here the authors show that allelic variation at rs6897932, an autoimmune GWAS risk allele at IL7R, regulates surface and soluble IL-7R in stimulated monocytes, indicating a function of monocytes in IL-7-related autoimmunity.

Hussein Al-Mossawi
Nicole Yager
Benjamin P. Fairfax
ResearchOpen Access08 Oct 2019
Nature Communications

Volume: 10, P: 1-11
SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout

Veronique Vitart
Igor Rudan
Alan F Wright
Research09 Mar 2008
Nature Genetics

Volume: 40, P: 437-442
Novel gene function revealed by mouse mutagenesis screens for models of age-related disease

Random mutagenesis can uncover novel genes involved in phenotypic traits. Here the authors perform a large-scale phenotypic screen on over 100 mouse strains generated by ENU mutagenesis to identify mice with age-related diseases, which they attribute to specific mutations revealed by whole-genome sequencing.

Paul K. Potter
Michael R. Bowl
Steve D. M. Brown
ResearchOpen Access18 Aug 2016
Nature Communications

Volume: 7, P: 1-13
Intranasal delivery of mRNA expressing newly identified Acinetobacter baumannii antigens protects against bacterial lung disease

Sophie L. Higham
Ziyin Wang
John S. Tregoning
ResearchOpen Access04 Jul 2025
npj Vaccines

Volume: 10, P: 1-14
Novel Monoclonal Antibody Recognition of Oxidative DNA Damage Adduct, Deoxycytidine-Glyoxal

Nalini Mistry
Ian Podmore
Joseph Lunec
Research01 Feb 2003
Laboratory Investigation

Volume: 83, P: 241-250
One thousand plant transcriptomes and the phylogenomics of green plants

The One Thousand Plant Transcriptomes Initiative provides a robust phylogenomic framework for examining green plant evolution that comprises the transcriptomes and genomes of diverse species of green plants.

James H. Leebens-Mack
Michael S. Barker
Gane Ka-Shu Wong
ResearchOpen Access23 Oct 2019
Nature

Volume: 574, P: 679-685
Aurora kinases: shining lights on the therapeutic horizon?

Paul D Andrews
Reviews28 Jul 2005
Oncogene

Volume: 24, P: 5005-5015
The Southern Ocean Exchange: porous boundaries between humpback whale breeding populations in southern polar waters

M. C. C. Marcondes
T. Cheeseman
R. S. Sousa-Lima
ResearchOpen Access08 Dec 2021
Scientific Reports

Volume: 11, P: 1-12
Massively parallel sequencing of mitochondrial genome in primary open angle glaucoma identifies somatically acquired mitochondrial mutations in ocular tissue

Neeru Amrita Vallabh
Brian Lane
Colin Willoughby
ResearchOpen Access01 Nov 2024
Scientific Reports

Volume: 14, P: 1-12
Segmentation and quantification of subcellular structures in fluorescence microscopy images using Squassh

Aurélien Rizk
Grégory Paul
Ivo F Sbalzarini
Protocols13 Feb 2014
Nature Protocols

Volume: 9, P: 586-596
A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms

Alan M. Jones
Isaac M. Westwood
Rob L. M. van Montfort
ResearchOpen Access06 Oct 2016
Scientific Reports

Volume: 6, P: 1-13
Flow virometry analysis of envelope glycoprotein conformations on individual HIV virions

Anush Arakelyan
Wendy Fitzgerald
Leonid Margolis
ResearchOpen Access19 Apr 2017
Scientific Reports

Volume: 7, P: 1-14
Improvement in patients' quality-of-life following strabismus surgery: evaluation of postoperative outcomes using the Adult Strabismus 20 (AS-20) score

P Glasman
R Cheeseman
J M Durnian
Research09 Aug 2013
Eye

Volume: 27, P: 1249-1253
Possible mediators of metabolic endotoxemia in women with obesity and women with obesity-diabetes in The Gambia

Modou Jobe
Schadrac C. Agbla
Andrew M. Prentice
ResearchOpen Access06 Aug 2022
International Journal of Obesity

Volume: 46, P: 1892-1900
Pooled genetic perturbation screens with image-based phenotypes

In this protocol, CRISPR perturbations are introduced in cells using lentiviral libraries and read out using in situ sequencing, coupling high-throughput pooled screening with phenotypic image readouts in live or fixed cells.

David Feldman
Luke Funk
Paul C. Blainey
Protocols12 Jan 2022
Nature Protocols

Volume: 17, P: 476-512
The dos and don’ts of influencing policy: a systematic review of advice to academics

Kathryn Oliver
Paul Cairney
ReviewsOpen Access19 Feb 2019
Palgrave Communications

Volume: 5, P: 1-11
iPhones for eye surgeons

A Bastawrous
R C Cheeseman
A Kumar
Editorial08 Mar 2012
Eye

Volume: 26, P: 343-354

Search

Prognostic Value of Serum Hyaluronic Acid and Type I and III Procollagen Propeptides in Extrahepatic Biliary Atresia

EB1 regulates attachment of Ska1 with microtubules by forming extended structures on the microtubule lattice

A genome-wide atlas of human cell morphology

Adaptive changes in the kinetochore architecture facilitate proper spindle assembly

Context-specific regulation of surface and soluble IL7R expression by an autoimmune risk allele

SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout

Novel gene function revealed by mouse mutagenesis screens for models of age-related disease

Intranasal delivery of mRNA expressing newly identified Acinetobacter baumannii antigens protects against bacterial lung disease

Novel Monoclonal Antibody Recognition of Oxidative DNA Damage Adduct, Deoxycytidine-Glyoxal

One thousand plant transcriptomes and the phylogenomics of green plants

Aurora kinases: shining lights on the therapeutic horizon?

The Southern Ocean Exchange: porous boundaries between humpback whale breeding populations in southern polar waters

Massively parallel sequencing of mitochondrial genome in primary open angle glaucoma identifies somatically acquired mitochondrial mutations in ocular tissue

Segmentation and quantification of subcellular structures in fluorescence microscopy images using Squassh

A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms

Flow virometry analysis of envelope glycoprotein conformations on individual HIV virions

Improvement in patients' quality-of-life following strabismus surgery: evaluation of postoperative outcomes using the Adult Strabismus 20 (AS-20) score

Possible mediators of metabolic endotoxemia in women with obesity and women with obesity-diabetes in The Gambia

Pooled genetic perturbation screens with image-based phenotypes

The dos and don’ts of influencing policy: a systematic review of advice to academics

iPhones for eye surgeons

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