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Showing 101–139 of 139 results

Advanced filters: Author: Paul Corey Clear advanced filters

Tumor cell-specific bioluminescence platform to identify stroma-induced changes to anticancer drug activity

McMillin et al. describe a drug screening platform that takes into account the tumor microenvironment, in particular tumor-stromal interactions, enabling the screening of the antitumor activity of candidate anticancer agents in the context of such interactions. The in vitro tumor cell–specific bioluminescence imaging assay is both high throughput and scalable.

Douglas W McMillin
Jake Delmore
Constantine S Mitsiades
Research14 Mar 2010
Nature Medicine

Volume: 16, P: 483-489
Establishing community reference samples, data and call sets for benchmarking cancer mutation detection using whole-genome sequencing

Tumor–normal paired DNA samples from a breast cancer cell line and a matched lymphoblastoid cell line enable calibration of clinical sequencing pipelines and benchmarking ‘tumor-only’ or ‘matched tumor–normal’ analyses.

Li Tai Fang
Bin Zhu
Yuanting Zheng
Research09 Sept 2021
Nature Biotechnology

Volume: 39, P: 1151-1160
Cyclic nucleotide-gated channels: shedding light on the opening of a channel pore

Galen E. Flynn
J. P. Johnson Jr
William N. Zagotta
Reviews01 Sept 2001
Nature Reviews Neuroscience

Volume: 2, P: 643-651
Chinese scientists and US leadership in the life sciences

Steven H. Holtzman
Ron Cohen
Shuguang Zhang
Correspondence03 Oct 2019
Nature Biotechnology

Volume: 37, P: 1261-1263
Interaction with cyclin-dependent kinases and PCNA modulates proteasome-dependent degradation of p21

Corinne Cayrol
Bernard Ducommun
Research12 Oct 1998
Oncogene

Volume: 17, P: 2437-2444
Transcriptional profiles of pulmonary artery endothelial cells in pulmonary hypertension

Navneet Singh
Carsten Eickhoff
Corey E. Ventetuolo
ResearchOpen Access18 Dec 2023
Scientific Reports

Volume: 13, P: 1-15
Building capacity for sustainable research programmes for cancer in Africa

In September 2012, over 100 experts in cancer research in Africa met in London to discuss the challenges in carrying out high-quality research in this continent. This Review summarizes the discussions and recommendations of this meeting and many examples of successful programmes that have enhanced the development of research in Africa. It also discusses the next steps required to create programmes that will enable evidenced-based cancer control approaches.

Isaac Adewole
Damali N. Martin
David J. Kerr
Reviews11 Mar 2014
Nature Reviews Clinical Oncology

Volume: 11, P: 251-259
Regulation and function of protein kinase B and MAP kinase activation by the IL-5/GM-CSF/IL-3 receptor

Pascale F Dijkers
Thamar B van Dijk
Paul J Coffer
Research14 Jun 1999
Oncogene

Volume: 18, P: 3334-3342
Computerised Dynamic Posturography in Premanifest and Manifest individuals with Huntington’s Disease

Alvaro Reyes
Danielle Salomonczyk
Travis Cruickshank
ResearchOpen Access02 Oct 2018
Scientific Reports

Volume: 8, P: 1-7
A worldwide study of white matter microstructural alterations in people living with Parkinson’s disease

Conor Owens-Walton
Talia M. Nir
Ysbrand van der Werf
ResearchOpen Access11 Aug 2024
npj Parkinson's Disease

Volume: 10, P: 1-12
Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours

A potent and selective catalytic inhibitor of p300/CBP histone acetyltransferases suppresses tumour proliferation across multiple cell lineages, illustrating the therapeutic potential of drug-like small molecules that target histone acetyltransferases.

Loren M. Lasko
Clarissa G. Jakob
Kenneth D. Bromberg
Research27 Sept 2017
Nature

Volume: 550, P: 128-132
Advancing the global public health agenda for NAFLD: a consensus statement

Non-alcoholic fatty liver disease (NAFLD) is a potentially serious liver disease with a substantial burden worldwide. In this Consensus Statement, a global multidisciplinary group of experts develop consensus statements and recommendations addressing a broad range of topics on NAFLD to raise awareness and spur action.

Jeffrey V. Lazarus
Henry E. Mark
Ming-Hua Zheng
Reviews27 Oct 2021
Nature Reviews Gastroenterology & Hepatology

Volume: 19, P: 60-78
Sustainable irrigation and climate feedbacks

Irrigation expansion is expected to meet increasing food demand and help agriculture adapt to climate change. This Review article synthesizes the various linkages between irrigation and climate, evaluating their impacts on each other and presenting innovative solutions for sustainable irrigation under climate change.

Yi Yang
Zhenong Jin
David B. Lobell
Reviews17 Aug 2023
Nature Food

Volume: 4, P: 654-663
Letters to the Editor: Response

Paul M Quinton
Correspondence01 May 1984
Pediatric Research

Volume: 18, P: 496-497
Biotech leaders call for free press

Ron Cohen
Steven Holtzman
Sanford Sandy Zweifach
Correspondence01 Oct 2018
Nature Biotechnology

Volume: 36, P: 920-922
Predicting chronic wasting disease in white-tailed deer at the county scale using machine learning

Md Sohel Ahmed
Brenda J. Hanley
Krysten L. Schuler
ResearchOpen Access22 Jun 2024
Scientific Reports

Volume: 14, P: 1-10
Instrumentally Detected Changes in Motor Functioning in Patients with Low Levels of Antipsychotic Dopamine D₂ Blockade

Paul B Fitzgerald
Shitij Kapur
Robert B Zipursky
Research01 Jan 2000
Neuropsychopharmacology

Volume: 22, P: 19-26
Letter

S P Harding
Correspondence01 May 1995
Eye

Volume: 9, P: 390-391
Pembrolizumab microgravity crystallization experimentation

Paul Reichert
Winifred Prosise
Corey Strickland
ResearchOpen Access02 Dec 2019
npj Microgravity

Volume: 5, P: 1-8
High-throughput screens identify HSP90 inhibitors as potent therapeutics that target inter-related growth and survival pathways in advanced prostate cancer

Keith H. Jansson
John B. Tucker
Kathleen Kelly
ResearchOpen Access22 Nov 2018
Scientific Reports

Volume: 8, P: 1-13
Expectations of life and health among spinal cord injured adults

Mary Ann McColl
Janice Walker
Paul Corey
Research01 Dec 1997
Spinal Cord

Volume: 35, P: 818-828
Machine learned interatomic potentials for ternary carbides trained on the AFLOW database

Josiah Roberts
Biswas Rijal
Eva Zurek
ResearchOpen Access02 Jul 2024
npj Computational Materials

Volume: 10, P: 1-10
Impact of depth of clinical response on outcomes of acute myeloid leukemia patients in first complete remission who undergo allogeneic hematopoietic cell transplantation

Mary-Elizabeth Percival
Hai-Lin Wang
Brenda M. Sandmaier
Research16 Apr 2021
Bone Marrow Transplantation

Volume: 56, P: 2108-2117
Host methylation predicts SARS-CoV-2 infection and clinical outcome

Konigsberg et al. profile DNA methylation in blood samples from SARS-CoV-2 cases and controls. The authors use machine learning to classify infected vs. non-infected individuals and predict clinical outcomes related to disease severity.

Iain R. Konigsberg
Bret Barnes
Kathleen C. Barnes
ResearchOpen Access26 Oct 2021
Communications Medicine

Volume: 1, P: 1-10
Oligonucleoside Methylphosphonates as Antisense Reagents

Paul S. Miller
Reviews01 Apr 1991
Bio/Technology

Volume: 9, P: 358-362
Activity-independent targeting of mTOR to lysosomes in primary osteoclasts

Andrew Wang
Luciene R. Carraro-Lacroix
Irina Voronov
ResearchOpen Access07 Jun 2017
Scientific Reports

Volume: 7, P: 1-12
A pure likelihood approach to the analysis of genetic association data: an alternative to Bayesian and frequentist analysis

Lisa J Strug
Susan E Hodge
Charles Rohde
Research28 Apr 2010
European Journal of Human Genetics

Volume: 18, P: 933-941
Gut microbial communities of hybridising pygmy angelfishes reflect species boundaries

Gut microbiomes of parent species of pygmy angelfishes were different from each other while hybrid individuals showed low differences to parents, suggesting shifts in gut microbiomes as early indicators of speciation in hybridising species.

Megan J. Huggett
Jean-Paul A. Hobbs
Joseph D. DiBattista
ResearchOpen Access18 May 2023
Communications Biology

Volume: 6, P: 1-9
Evaluation of body mass index percentiles for assessment of malnutrition in children with cystic fibrosis

B Wiedemann
K D Paul
T O Hirche
Research10 Jan 2007
European Journal of Clinical Nutrition

Volume: 61, P: 759-768
An adapted European LeukemiaNet genetic risk stratification for acute myeloid leukemia patients undergoing allogeneic hematopoietic cell transplant. A CIBMTR analysis

Antonio M. Jimenez Jimenez
Marcos De Lima
Daniel Weisdorf
Research28 Sept 2021
Bone Marrow Transplantation

Volume: 56, P: 3068-3077
Regulation of the unfolded protein response through ATF4 and FAM129A in prostate cancer

Nora Pällmann
Marte Livgård
Fahri Saatcioglu
Research16 Jul 2019
Oncogene

Volume: 38, P: 6301-6318
The interplay between Src family kinases and receptor tyrosine kinases

Paul A Bromann
Hasan Korkaya
Sara A Courtneidge
Reviews18 Oct 2004
Oncogene

Volume: 23, P: 7957-7968
Development of models to predict dose of pesticides in professional turf applicators

SHELLEY A HARRIS
ANDREA M SASS-KORTSAK
JAMES T PURDHAM
Research24 Apr 2002
Journal of Exposure Science & Environmental Epidemiology

Volume: 12, P: 130-144
Correction to: Impact of depth of clinical response on outcomes of acute myeloid leukemia patients in first complete remission who undergo allogeneic hematopoietic cell transplantation

Mary-Elizabeth Percival
Hai-Lin Wang
Brenda M. Sandmaier
Amendments and Corrections20 May 2021
Bone Marrow Transplantation

Volume: 56, P: 2319
Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions

Solveig K. Sieberts
Thanneer M. Perumal
Lara M. Mangravite
ResearchOpen Access12 Oct 2020
Scientific Data

Volume: 7, P: 1-11
Cystic fibrosis modifier genes related to Pseudomonas aeruginosa infection

J E Park
R Yung
A J Sandford
Research27 Jan 2011
Genes & Immunity

Volume: 12, P: 370-377
Long-term dataset on aquatic responses to concurrent climate change and recovery from acidification

Taylor H. Leach
Luke A. Winslow
Kevin C. Rose
ResearchOpen Access10 Apr 2018
Scientific Data

Volume: 5, P: 1-12
International recommendations for screening and preventative practices for long-term survivors of transplantation and cellular therapy: a 2023 update

Seth J. Rotz
Neel S. Bhatt
Rachel Phelan
Reviews27 Feb 2024
Bone Marrow Transplantation

Volume: 59, P: 717-741
Multigenerational hybridisation and its consequences for maternal effects in Atlantic salmon

P V Debes
D J Fraser
J A Hutchings
Research08 May 2013
Heredity

Volume: 111, P: 238-247

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